Developmental Biology

Anti-TAF7L Antibody (CAB15455)

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SKU:
CAB15455
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-TAF7L Antibody
Antibody SKU:CAB15455
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 363-462 of human TAF7L (NP_079161.3).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 363-462 of human TAF7L (NP_079161.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SEEY LERQ LQAE FIES GQYR ANEG TSSI VMEI QKQI EKKE KKLH KIQN KAQR QKDL IMKV ENLT LKNH FQSV LEQL ELQE KQKN EKLI SLQE QLQR FLKK
Gene ID:54457
Uniprot:Q5H9L4
Cellular Location:Cytoplasm, Nucleus
Calculated MW:34kDa/43kDa/52kDa
Observed MW:Refer to figures
Synonyms:TAF7L, CT40, TAF2Q
Background:This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:TAF7L: Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis. Belongs to the TAF7 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cancer Testis Antigen (CTA); DNA-binding

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: transcription factor TFIID complex

Molecular Function:histone acetyltransferase binding; transcription coactivator activity; transcription factor binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcriptional preinitiation complex assembly

NCBI Summary:This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
UniProt Code:Q5H9L4
NCBI GenInfo Identifier:74762183
NCBI Gene ID:54457
NCBI Accession:Q5H9L4.1
UniProt Secondary Accession:Q5H9L4,Q5H9L6, Q86XI4, Q9BXU5, Q9H5R0,
UniProt Related Accession:Q5H9L4
Molecular Weight:34,726 Da
NCBI Full Name:Transcription initiation factor TFIID subunit 7-like
NCBI Synonym Full Names:TATA-box binding protein associated factor 7 like
NCBI Official Symbol:TAF7L  
NCBI Official Synonym Symbols:CT40; TAF2Q  
NCBI Protein Information:transcription initiation factor TFIID subunit 7-like
UniProt Protein Name:Transcription initiation factor TFIID subunit 7-like
UniProt Synonym Protein Names:Cancer/testis antigen 40; CT40; RNA polymerase II TBP-associated factor subunit Q; TATA box-binding protein-associated factor 50 kDa; Transcription initiation factor TFIID 50 kDa subunit
Protein Family:Transcription initiation factor
UniProt Gene Name:TAF7L  
UniProt Entry Name:TAF7L_HUMAN
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