Anti-Syntaxin 3 Antibody (CAB3712)
- SKU:
- CAB3712
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- STX3A
Description
| Product Name: | Syntaxin 3 Rabbit mAb |
| Product Code: | CAB3712 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | STX3A |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Syntaxin 3 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, 293T, PC-12 |
| Immunogen: | A synthesized peptide derived from human Syntaxin 3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6809 |
| Uniprot: | Q13277 |
| Cellular Location: | Membrane, Single-pass type IV membrane protein |
| Calculated MW: | 33kDa |
| Observed MW: | 35kDa |
| UniProt Protein Function: | STX3: Potentially involved in docking of synaptic vesicles at presynaptic active zones. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q12.1 Cellular Component: apical plasma membrane; azurophil granule; growth cone; integral to membrane; intercellular junction; lamellipodium; neuron projection; plasma membrane; SNARE complex; specific granule; synaptic vesicle; vacuole Molecular Function:arachidonic acid binding; protein binding; SNAP receptor activity; SNARE binding Biological Process: intracellular protein transport; neurite development; positive regulation of cell adhesion; positive regulation of cell proliferation; positive regulation of chemotaxis; synaptic vesicle fusion to presynaptic membrane; vesicle docking |
| NCBI Summary: | The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | Q13277 |
| NCBI GenInfo Identifier: | 116242806 |
| NCBI Gene ID: | 6809 |
| NCBI Accession: | Q13277.3 |
| UniProt Secondary Accession: | Q13277,O43750, O43751, Q15360, B4DME0, |
| UniProt Related Accession: | Q13277 |
| Molecular Weight: | 32,018 Da |
| NCBI Full Name: | Syntaxin-3 |
| NCBI Synonym Full Names: | syntaxin 3 |
| NCBI Official Symbol: | STX3 |
| NCBI Official Synonym Symbols: | STX3A |
| NCBI Protein Information: | syntaxin-3 |
| UniProt Protein Name: | Syntaxin-3 |
| Protein Family: | Syntaxin |
| UniProt Gene Name: | STX3 |
| UniProt Entry Name: | STX3_HUMAN |
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