Cell Biology Antibodies 12
Anti-Synaptogyrin-1 Antibody (CAB8175)
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- SKU:
- CAB8175
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | SYNGR1 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8175 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human SYNGR1 (NP_663783.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human SYNGR1 (NP_663783.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEGG AYGA GKAG GAFD PYTL VRQP HTIL RVVS WLFS IVVF GSIV NEGY LNSA SEGE EFCI YNRN PNAC SYGV AVGV LAFL TCLL YLAL DVYF PQIS SVKD RKKA VLSD IGVS AFWA FLWF VGFC YLAN QWQV SKPK DNPL NEGT DAAR AAIA FSFF SIFT WSLT AALA VRRF KDLS FQEE YSTL FPAS AQP |
| Gene ID: | 9145 |
| Uniprot: | O43759 |
| Cellular Location: | Cell junction, Melanosome, Membrane, Multi-pass membrane protein, synapse |
| Calculated MW: | 21kDa/25kDa |
| Observed MW: | 25kDa |
| Synonyms: | SYNGR1 |
| Background: | This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. |
| UniProt Protein Function: | SYNGR1: Involved in the regulation of short-term and long-term synaptic plasticity. Belongs to the synaptogyrin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: neuromuscular junction; synaptic vesicle membrane Molecular Function:protein binding Biological Process: regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity |
| NCBI Summary: | This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43759 |
| NCBI GenInfo Identifier: | 115502453 |
| NCBI Gene ID: | 9145 |
| NCBI Accession: | O43759.2 |
| UniProt Secondary Accession: | O43759,O43757, O43758, Q53Y02, Q96J56, Q9UGZ4, A6NP69 A8K0E2, |
| UniProt Related Accession: | O43759 |
| Molecular Weight: | 21,591 Da |
| NCBI Full Name: | Synaptogyrin-1 |
| NCBI Synonym Full Names: | synaptogyrin 1 |
| NCBI Official Symbol: | SYNGR1 |
| NCBI Protein Information: | synaptogyrin-1 |
| UniProt Protein Name: | Synaptogyrin-1 |
| Protein Family: | Synaptogyrin |
| UniProt Gene Name: | SYNGR1 |
| UniProt Entry Name: | SNG1_HUMAN |
 | Western blot analysis of extracts of mouse pancreas, using SYNGR1 antibody (CAB8175) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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