Neuroscience

Anti-SV2C Antibody (CAB16268)

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SKU:
CAB16268
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

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Antibody Name:Anti-SV2C Antibody
Antibody SKU:CAB16268
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 460-580 of human SV2C (NP_055794.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 460-580 of human SV2C (NP_055794.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PLQS DEYA LLTR NVER DKYA NFTI NFTM ENQI HTGM EYDN GRFI GVKF KSVT FKDS VFKS CTFE DVTS VNTY FKNC TFID TVFD NTDF EPYK FIDS EFKN CSFF HNKT GCQI TFDD DYSA Y
Gene ID:22987
Uniprot:Q496J9
Cellular Location:Cytoplasmic vesicle, Multi-pass membrane protein, secretory vesicle, synaptic vesicle membrane
Calculated MW:82kDa
Observed MW:Refer to figures
Synonyms:SV2C
Background:
UniProt Protein Function:SV2C: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. Belongs to the major facilitator superfamily.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: synaptic vesicle; synaptic vesicle membrane; integral to membrane; plasma membrane; cell junction

Molecular Function:transmembrane transporter activity

Biological Process: neurotransmitter transport; pathogenesis; transmembrane transport

UniProt Code:Q496J9
NCBI GenInfo Identifier:108860965
NCBI Gene ID:22987
NCBI Accession:Q496J9.1
UniProt Secondary Accession:Q496J9,Q496K1, Q9UPU8,
UniProt Related Accession:Q496J9
Molecular Weight:727
NCBI Full Name:Synaptic vesicle glycoprotein 2C
NCBI Synonym Full Names:synaptic vesicle glycoprotein 2C
NCBI Official Symbol:SV2C  
NCBI Protein Information:synaptic vesicle glycoprotein 2C; synaptic vesicle protein 2C
UniProt Protein Name:Synaptic vesicle glycoprotein 2C
Protein Family:Synaptic vesicle glycoprotein
UniProt Gene Name:SV2C  
UniProt Entry Name:SV2C_HUMAN
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