Anti-SRD5A2 Antibody (CAB19762)
- SKU:
- CAB19762
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Product Name: | SRD5A2 Rabbit mAb |
| Product Code: | CAB19762 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SRD5A2 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, Mouse liver, Mouse testis, Mouse kidney, Rat testis, Rat kidney |
| Immunogen: | A synthesized peptide derived from human SRD5A2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6716 |
| Uniprot: | P31213 |
| Calculated MW: | 28kDa |
| Observed MW: | 28KDa |
| UniProt Protein Function: | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| NCBI Summary: | This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008] |
| UniProt Code: | P31213 |
| NCBI GenInfo Identifier: | 39812447 |
| NCBI Gene ID: | 6716 |
| NCBI Accession: | NP_000339.2 |
| UniProt Secondary Accession: | P31213,Q2M1R4, Q9BYE6, B2RE87, |
| UniProt Related Accession: | P31213 |
| Molecular Weight: | 27 |
| NCBI Full Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
| NCBI Synonym Full Names: | steroid 5 alpha-reductase 2 |
| NCBI Official Symbol: | SRD5A2 |
| NCBI Protein Information: | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
| UniProt Protein Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 |
| UniProt Synonym Protein Names: | 5 alpha-SR2; SR type 2; Steroid 5-alpha-reductase 2; S5AR 2; Type II 5-alpha reductase |
| UniProt Gene Name: | SRD5A2 |
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