Developmental Biology

Anti-SRD5A1 Antibody (CAB14787)

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SKU:
CAB14787
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-SRD5A1 Antibody
Antibody SKU:CAB14787
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Mouse liver, Mouse testis, Rat liver
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LIYP FLMR GGKP MPLL ACTM AIMF CTCN GYLQ SRYL SHCA VYAD DWVT DPRF LIGF GLWL TGML INIH SDHI LRNL RKPG DTGY KIPR GGLF EYVT AANY F
Gene ID:6715
Uniprot:P18405
Cellular Location:Endoplasmic reticulum membrane, Microsome membrane, Multi-pass membrane protein
Calculated MW:29kDa
Observed MW:29kDa
Synonyms:SRD5A1, S5AR 1, S5AR1
Background:
UniProt Protein Function:Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
NCBI Summary:Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
UniProt Code:P18405
NCBI GenInfo Identifier:4507201
NCBI Gene ID:6715
NCBI Accession:NP_001038.1
UniProt Secondary Accession:P18405,Q9UHY4, Q9UP36, Q9UP37, B2R7Q1,
UniProt Related Accession:P18405
Molecular Weight:28
NCBI Full Name:3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform 1
NCBI Synonym Full Names:steroid 5 alpha-reductase 1
NCBI Official Symbol:SRD5A1  
NCBI Official Synonym Symbols:S5AR 1  
NCBI Protein Information:3-oxo-5-alpha-steroid 4-dehydrogenase 1
UniProt Protein Name:3-oxo-5-alpha-steroid 4-dehydrogenase 1
UniProt Synonym Protein Names:SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
UniProt Gene Name:SRD5A1  
Anti-SRD5A1 Antibody (CAB14787)Western blot analysis of extracts of various cell lines, using SRD5A1 antibody (CAB14787) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
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