Metabolism Antibodies 3
Anti-SQS/FDFT1 Antibody (CAB4651)
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- SKU:
- CAB4651
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DGPT
- Synonyms:
- ERG9
- Synonyms:
- SQS
- Synonyms:
- SS
- Research Area:
- Metabolism
Description
| Product Name: | SQS/FDFT1 Rabbit mAb |
| Product Code: | CAB4651 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DGPT, ERG9, SQS, SS |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SQS/FDFT1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, U-251MG, Mouse kidney, Rat liver |
| Immunogen: | A synthesized peptide derived from human SQS/FDFT1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2222 |
| Uniprot: | P37268 |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 48kDa |
| Observed MW: | 48KDa |
| UniProt Protein Function: | FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 2.5.1.21; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; Transferase; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 8p23.1-p22 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane Molecular Function:farnesyl-diphosphate farnesyltransferase activity Biological Process: cholesterol biosynthetic process; steroid biosynthetic process |
| NCBI Summary: | This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P37268 |
| NCBI GenInfo Identifier: | 585126 |
| NCBI Gene ID: | 2222 |
| NCBI Accession: | P37268.1 |
| UniProt Secondary Accession: | P37268,Q96GT0, B3KQ95, B4DJE5, B4DT56, B7Z1J3, |
| UniProt Related Accession: | P37268 |
| Molecular Weight: | 43,060 Da |
| NCBI Full Name: | Squalene synthase |
| NCBI Synonym Full Names: | farnesyl-diphosphate farnesyltransferase 1 |
| NCBI Official Symbol: | FDFT1 |
| NCBI Official Synonym Symbols: | SS; SQS; DGPT; ERG9 |
| NCBI Protein Information: | squalene synthase |
| UniProt Protein Name: | Squalene synthase |
| UniProt Synonym Protein Names: | FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase |
| UniProt Gene Name: | FDFT1 |
| UniProt Entry Name: | FDFT_HUMAN |
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