Signal Transduction Antibodies 2
Anti-SLC8A2 Antibody (CAB15723)
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- SKU:
- CAB15723
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC8A2 Antibody |
| Antibody SKU: | CAB15723 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human SLC8A2 (NP_055878.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LMTG AGNV LRRH AADA SRRA APAE GAGE DEDD GASR IFFE PSLY HCLE NCGS VLLS VTCQ GGEG NSTF YVDY RTED GSAK AGSD YEYS EGT |
| Gene ID: | 6543 |
| Uniprot: | Q9UPR5 |
| Cellular Location: | Basolateral cell membrane, Cell membrane, Cell projection, Multi-pass membrane protein, Perikaryon, dendrite, dendritic spine |
| Calculated MW: | 100kDa |
| Observed MW: | 100kDa |
| Synonyms: | SLC8A2, NCX2 |
| Background: |
| UniProt Protein Function: | Mediates the electrogenic exchange of Ca2+ against Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes. Contributes to cellular Ca2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca2+ and Na+ excretion. |
| UniProt Code: | Q9UPR5 |
| NCBI GenInfo Identifier: | 57163987 |
| NCBI Gene ID: | 6543 |
| NCBI Accession: | NP_055878.1 |
| UniProt Secondary Accession: | Q9UPR5,B4DYQ9, |
| UniProt Related Accession: | Q9UPR5 |
| Molecular Weight: | 101 |
| NCBI Full Name: | sodium/calcium exchanger 2 |
| NCBI Synonym Full Names: | solute carrier family 8 member A2 |
| NCBI Official Symbol: | SLC8A2 |
| NCBI Official Synonym Symbols: | NCX2 |
| NCBI Protein Information: | sodium/calcium exchanger 2 |
| UniProt Protein Name: | Sodium/calcium exchanger 2 |
| UniProt Synonym Protein Names: | Na(+)/Ca(2+)-exchange protein 2; Solute carrier family 8 member 2 |
| Protein Family: | PsbD mRNA maturation factor |
| UniProt Gene Name: | SLC8A2 |
 | Western blot analysis of extracts of various cell lines, using SLC8A2 antibody (CAB15723) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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