Signal Transduction Antibodies 1

Anti-SLC22A23 Antibody (CAB14419)

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SKU:
CAB14419
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC22A23 Antibody
Antibody SKU:CAB14419
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 336-405 of human SLC22A23 (NP_068764.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, Jurkat, Mouse kidney, Mouse liver, Rat liver, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 336-405 of human SLC22A23 (NP_068764.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LLPE SRDQ NLPE NISN GEHY TRQP LLPH KKGE QPLL LTNA ELKD YSGL HDAA AAGD TLPE GATA NGMK AM
Gene ID:63027
Uniprot:A1A5C7
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:34kDa/38kDa/44kDa/73kDa
Observed MW:74kDa
Synonyms:SLC22A23, C6orf85
Background:
UniProt Protein Function:SLC22A23: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p25.2

Cellular Component: integral to plasma membrane

Molecular Function:organic anion transmembrane transporter activity; protein binding

NCBI Summary:SLC22A23 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
UniProt Code:A1A5C7
NCBI GenInfo Identifier:118764064
NCBI Gene ID:63027
NCBI Accession:BC128580
UniProt Secondary Accession:A1A5C7,Q5T8B8, Q6ZMH3, Q8IW73, A1A5C8,
UniProt Related Accession:A1A5C7
Molecular Weight:38,049 Da
NCBI Full Name:Homo sapiens solute carrier family 22, member 23, mRNA
NCBI Synonym Full Names:solute carrier family 22 member 23
NCBI Official Symbol:SLC22A23  
NCBI Official Synonym Symbols:C6orf85  
NCBI Protein Information:solute carrier family 22 member 23
UniProt Protein Name:Solute carrier family 22 member 23
Protein Family:Solute carrier family
UniProt Gene Name:SLC22A23  
UniProt Entry Name:S22AN_HUMAN
Anti-SLC22A23 Antibody (CAB14419)Western blot analysis of extracts of various cell lines, using SLC22A23 antibody (CAB14419) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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