Cell Biology Antibodies 3
Anti-SIGLEC6 Antibody (CAB12387)
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- SKU:
- CAB12387
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SIGLEC6 Antibody |
| Antibody SKU: | CAB12387 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QERR FQLE GPES LTVQ EGLC VLVP CRLP TTLP ASYY GYGY WFLE GADV PVAT NDPD EEVQ EETR GRFH LLWD PRRK NCSL SIRD ARRR DNAA YFFR LKSK WMKY GYTS SKLS VRVM ALTH RPNI SIPG TLES GHPS NLTC SVPW VCEQ GTPP IFSW MSAA PTSL GPRT TQSS VLTI TPRP QDHS TNLT CQVT FP |
| Gene ID: | 946 |
| Uniprot: | O43699 |
| Cellular Location: | Cell membrane, Secreted, Single-pass type I membrane protein |
| Calculated MW: | 37kDa/38kDa/42kDa/44kDa/48kDa/49kDa |
| Observed MW: | 50kDa |
| Synonyms: | SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1 |
| Background: |
| UniProt Protein Function: | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| NCBI Summary: | This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016] |
| UniProt Code: | O43699 |
| NCBI GenInfo Identifier: | 215273884 |
| NCBI Gene ID: | 946 |
| NCBI Accession: | O43699.2 |
| UniProt Secondary Accession: | O43699,O15388, O43700, A8MV71, B2RTS8, C9JBE5, F8WA78 |
| UniProt Related Accession: | O43699 |
| Molecular Weight: | 44,348 Da |
| NCBI Full Name: | Sialic acid-binding Ig-like lectin 6 |
| NCBI Synonym Full Names: | sialic acid binding Ig like lectin 6 |
| NCBI Official Symbol: | SIGLEC6 |
| NCBI Official Synonym Symbols: | CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327 |
| NCBI Protein Information: | sialic acid-binding Ig-like lectin 6 |
| UniProt Protein Name: | Sialic acid-binding Ig-like lectin 6 |
| UniProt Synonym Protein Names: | CD33 antigen-like 1; CDw327; Obesity-binding protein 1; OB-BP1; CD_antigen: CD327 |
| Protein Family: | Sialic acid-binding Ig-like lectin |
| UniProt Gene Name: | SIGLEC6 |
 | Western blot analysis of extracts of mouse kidney, using SIGLEC6 antibody (CAB12387) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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