Immunology Antibodies 1

Alpha-1 Antichymotrypsin (SERPINA3) Rabbit Polyclonal Antibody (CAB1021)

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SKU:
CAB1021
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Synonyms:
ACT, AACT, GIG24, GIG25, Alpha-1 Antichymotrypsin (SERPINA3)
Research Use:
Immunology
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Description

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Alpha-1 Antichymotrypsin (SERPINA3) Antibody (CAB1021)

The Alpha-1 Antichymotrypsin (SERPINA3) Antibody (CAB1021) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.SERPINA3, also known as alpha-1-antichymotrypsin, is a serine protease inhibitor believed to play a role in regulating protease activity and protecting tissues from damage. Its diverse functions in the body make it a promising target for research in fields such as immunology, oncology, and neurology.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:Alpha-1 Antichymotrypsin (SERPINA3) Antibody
SKU:CAB1021
Size:20μL, 100μL
Reactivity:Human
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:HPNS PLDE ENLT QENQ DRGT HVDL GLAS ANVD FAFS LYKQ LVLK APDK NVIF SPLS ISTA LAFL SLGA HNTT LTEI LKGL KFNL TETS EAEI HQSF QHLL RTLN QSSD ELQL SMGN AMFV KEQL SLLD RFTE DAKR LYGS EAFA TDFQ DSAA AKKL INDY VKNG TRGK ITDL IKDL DSQT MMVL VNYI FFKA KWEM PFDP QDTH QSRF YLSK KKWV MVPM MSLH HLTI PYFR DEEL SCTV VELK YTGN ASAL FILP DQDK MEEV EAML LPET LKRW RDSL EFRE IGEL YLPK FSIS RDYN LNDI LLQL GIEE AFTS KADL SGIT GARN LAVS QVVH KAVL DVFE EGTE ASAA TAVK ITLL SALV ETRT IVRF NRPF LMII VPTD TQNI FFMS KVTN PKQA
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:100 - 1:500
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ACT, AACT, GIG24, GIG25, Alpha-1 Antichymotrypsin (SERPINA3)
Positive Sample:MCF7, U2OS
Cellular Localization:Secreted.
Calculated MW:48kDa
Observed MW:50-76kDa

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Purification MethodAffinity purification
Gene ID12
RRIDAB_2757732
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using Alpha-1 Antichymotrypsin (SERPINA3) Rabbit pAb (CAB1021) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human prostate cancer tissue using Alpha-1 Antichymotrypsin (SERPINA3) Rabbit pAb (CAB1021) at a dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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