Cell Biology Antibodies 15
Anti-SEC62 Antibody (CAB18589)
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- SKU:
- CAB18589
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SEC62 Antibody |
| Antibody SKU: | CAB18589 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human SEC62. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, MCF7 |
| Immunogen: | Recombinant protein of human SEC62. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7095 |
| Uniprot: | Q99442 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 52kDa |
 | Western blot - SEC62 Rabbit pAb (CAB18589) |
| Synonyms: | Dtrp1, HTP1, TLOC1, TP-1, SEC62 |
| Background: |
| UniProt Protein Function: | SEC62: a multi-pass membrane protein and component of the Sec61 complex of the rough endoplasmic reticulum membrane. The Sec61 complex may perform post-translational protein translocation into the ER and backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass; Channel, misc. Chromosomal Location of Human Ortholog: 3q26.2 Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; intermediate filament cytoskeleton; membrane; rough endoplasmic reticulum Molecular Function:receptor activity Biological Process: cotranslational protein targeting to membrane; posttranslational protein targeting to membrane |
| NCBI Summary: | The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99442 |
| NCBI GenInfo Identifier: | 74732781 |
| NCBI Gene ID: | 7095 |
| NCBI Accession: | Q99442.1 |
| UniProt Secondary Accession: | Q99442,O00682, O00729, D3DNQ0, |
| UniProt Related Accession: | Q99442 |
| Molecular Weight: | 45,862 Da |
| NCBI Full Name: | Translocation protein SEC62 |
| NCBI Synonym Full Names: | SEC62 homolog, preprotein translocation factor |
| NCBI Official Symbol: | SEC62 |
| NCBI Official Synonym Symbols: | HTP1; TP-1; Dtrp1; TLOC1 |
| NCBI Protein Information: | translocation protein SEC62 |
| UniProt Protein Name: | Translocation protein SEC62 |
| UniProt Synonym Protein Names: | Translocation protein 1; TP-1; hTP-1 |
| Protein Family: | Translocation protein |
| UniProt Gene Name: | SEC62 |
| UniProt Entry Name: | SEC62_HUMAN |
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