Anti-SAR1B Antibody (CAB4712)

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SKU:
CAB4712
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG

Description

Antibody Name:Anti-SAR1B Antibody (CAB4712)
Antibody SKU:CAB4712
Antibody Size:50µL, 100µL
Application:Western blotting
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SAR1B (NP_057187.1).
Application:Western blotting
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SAR1B (NP_057187.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSFI FDWI YSGF SSVL QFLG LYKK TGKL VFLG LDNA GKTT LLHM LKDD RLGQ HVPT LHPT SEEL TIAG MTFT TFDL GGHV QARR VWKN YLPA INGI VFLV DCAD HERL LESK EELD SLMT DETI ANVP ILIL GNKI DRPE AISE ERLR EMFG LYGQ TTGK GSIS LKEL NARP LEVF MCSV LKRQ GYGE GFRW MAQY ID
Cellular Location:Endoplasmic reticulum membrane, Golgi apparatus, Golgi stack membrane, Peripheral membrane protein
Calculated MW:22kDa
Observed MW:Refer to figures
Synonyms:SAR1B, ANDD, CMRD, GTBPB, SARA2
Background:The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
Western blot analysis of extracts of MCF-7 cells, using SAR1B antibody . Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Western blot analysis of extracts of MCF-7 cells, using SAR1B antibody . Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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