Signal Transduction Antibodies 1
Anti-S100A2 Antibody (CAB12647)
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- SKU:
- CAB12647
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-S100A2 Antibody |
| Antibody SKU: | CAB12647 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A2 (NP_005969.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | MCF7, SKOV3, A-431, HeLa, Mouse uterus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A2 (NP_005969.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MCSS LEQA LAVL VTTF HKYS CQEG DKFK LSKG EMKE LLHK ELPS FVGE KVDE EGLK KLMG SLDE NSDQ QVDF QEYA VFLA LITV MCND FFQG CPDR P |
| Gene ID: | 6273 |
| Uniprot: | P29034 |
| Cellular Location: | |
| Calculated MW: | 11kDa |
| Observed MW: | 11-15kDa |
| Synonyms: | S100A2, CAN19, S100L |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. |
| UniProt Protein Function: | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth. |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P29034 |
| NCBI GenInfo Identifier: | 5174661 |
| NCBI Gene ID: | 6273 |
| NCBI Accession: | NP_005969.1 |
| UniProt Secondary Accession: | P29034,O00266, Q3KRB9, Q5RHS8, Q9BU83, |
| UniProt Related Accession: | P29034 |
| Molecular Weight: | 10 |
| NCBI Full Name: | protein S100-A2 |
| NCBI Synonym Full Names: | S100 calcium binding protein A2 |
| NCBI Official Symbol: | S100A2 |
| NCBI Official Synonym Symbols: | CAN19; S100L |
| NCBI Protein Information: | protein S100-A2 |
| UniProt Protein Name: | Protein S100-A2 |
| UniProt Synonym Protein Names: | CAN19; Protein S-100L; S100 calcium-binding protein A2 |
| UniProt Gene Name: | S100A2 |
 | Western blot analysis of extracts of various cell lines, using S100A2 antibody (CAB12647) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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