Name: Anti-S100A2 Antibody (CAB12647)
Brand: Signal Transduction Antibodies 1
SKU: CAB12647
Availability: OutOfStock

Antibody Name:	Anti-S100A2 Antibody
Antibody SKU:	CAB12647
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A2 (NP_005969.1).

Application:	WB
Recommended Dilution:	WB 1:1000 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	MCF7, SKOV3, A-431, HeLa, Mouse uterus

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A2 (NP_005969.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MCSS LEQA LAVL VTTF HKYS CQEG DKFK LSKG EMKE LLHK ELPS FVGE KVDE EGLK KLMG SLDE NSDQ QVDF QEYA VFLA LITV MCND FFQG CPDR P
Gene ID:	6273
Uniprot:	P29034
Cellular Location:
Calculated MW:	11kDa
Observed MW:	11-15kDa

Synonyms:

S100A2, CAN19, S100L

Background:

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.

UniProt Protein Function:	May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
NCBI Summary:	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008]
UniProt Code:	P29034
NCBI GenInfo Identifier:	5174661
NCBI Gene ID:	6273
NCBI Accession:	NP_005969.1
UniProt Secondary Accession:	P29034,O00266, Q3KRB9, Q5RHS8, Q9BU83,
UniProt Related Accession:	P29034
Molecular Weight:	10
NCBI Full Name:	protein S100-A2
NCBI Synonym Full Names:	S100 calcium binding protein A2
NCBI Official Symbol:	S100A2
NCBI Official Synonym Symbols:	CAN19; S100L
NCBI Protein Information:	protein S100-A2
UniProt Protein Name:	Protein S100-A2
UniProt Synonym Protein Names:	CAN19; Protein S-100L; S100 calcium-binding protein A2
UniProt Gene Name:	S100A2

Western blot analysis of extracts of various cell lines, using S100A2 antibody (CAB12647) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.

ELISA Kits

Human S100A2 ELISA Kit

Human Protein S100-A2 (S100A2) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)