Cell Biology Antibodies 5
Anti-S100A10 Antibody (CAB14658)
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- SKU:
- CAB14658
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-S100A10 Antibody |
| Antibody SKU: | CAB14658 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A10 (NP_002957.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, VERO, HeLa, A-549, NIH/3T3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-97 of human S100A10 (NP_002957.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPSQ MEHA METM MFTF HKFA GDKG YLTK EDLR VLME KEFP GFLE NQKD PLAV DKIM KDLD QCRD GKVG FQSF FSLI AGLT IACN DYFV VHMK QKGK K |
| Gene ID: | 6281 |
| Uniprot: | P60903 |
| Cellular Location: | |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
| Synonyms: | S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10 |
| Background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. |
| UniProt Protein Function: | S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family. |
| UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 1q21 Cellular Component: extrinsic to plasma membrane; lipid raft Molecular Function:protein binding; protein homodimerization activity; calcium ion binding; lipid binding Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P60903 |
| NCBI GenInfo Identifier: | 46397706 |
| NCBI Gene ID: | 6281 |
| NCBI Accession: | P60903.2 |
| UniProt Related Accession: | P60903 |
| Molecular Weight: | 11kDa |
| NCBI Full Name: | Protein S100-A10 |
| NCBI Synonym Full Names: | S100 calcium binding protein A10 |
| NCBI Official Symbol: | S100A10 |
| NCBI Official Synonym Symbols: | 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG |
| NCBI Protein Information: | protein S100-A10 |
| UniProt Protein Name: | Protein S100-A10 |
| UniProt Synonym Protein Names: | Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A10 |
| UniProt Entry Name: | S10AA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using S100A10 antibody (CAB14658) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human colon using S100A10 antibody (CAB14658) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse testis using S100A10 antibody (CAB14658) at dilution of 1:100 (40x lens). |
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