Anti-RIOX2/MINA53 Antibody (CAB19809)

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SKU:
CAB19809
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
JMJD10
Synonyms:
MDIG
Synonyms:
MINA
Synonyms:
MINA53
Synonyms:
NO52
Synonyms:
ROX
Research Area:
Cell Biology

Description

Product Name:RIOX2/MINA53 Rabbit mAb
Product Code:CAB19809
Size:20uL, 50uL, 100uL
Synonyms:JMJD10, MDIG, MINA, MINA53, NO52, ROX
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human RIOX2/RIOX2/MINA53
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:BxPC-3, Mouse testis, Rat testis
Immunogen:A synthesized peptide derived from human RIOX2/RIOX2/MINA53
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:84864
Uniprot:Q8IUF8
Calculated MW:53kDa
Observed MW:53KDa
UniProt Protein Function:MINA: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Belongs to the MINA53/NO66 family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleolus

Chromosomal Location of Human Ortholog: 3q11.2

Cellular Component: transcription factor complex; cytoplasm; nucleolus; cytosol; nucleus

Molecular Function:dioxygenase activity; metal ion binding

Biological Process: transcription, DNA-dependent; ribosome biogenesis and assembly; negative regulation of transcription from RNA polymerase II promoter

NCBI Summary:MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008]
UniProt Code:Q8IUF8
NCBI GenInfo Identifier:74750624
NCBI Gene ID:84864
NCBI Accession:Q8IUF8.1
UniProt Related Accession:Q8IUF8
Molecular Weight:
NCBI Full Name:Ribosomal oxygenase 2
NCBI Synonym Full Names:ribosomal oxygenase 2
NCBI Official Symbol:RIOX2  
NCBI Official Synonym Symbols:ROX; MDIG; MINA; NO52; JMJD10; MINA53  
NCBI Protein Information:ribosomal oxygenase 2
UniProt Protein Name:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
UniProt Synonym Protein Names:60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX
Protein Family:Bifunctional lysine-specific demethylase and histidyl-hydroxylase
UniProt Gene Name:MINA  
UniProt Entry Name:MINA_HUMAN
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