Anti-RIOX2/MINA53 Antibody (CAB19809)
- SKU:
- CAB19809
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- JMJD10
- Synonyms:
- MDIG
- Synonyms:
- MINA
- Synonyms:
- MINA53
- Synonyms:
- NO52
- Synonyms:
- ROX
- Research Area:
- Cell Biology
Description
| Product Name: | RIOX2/MINA53 Rabbit mAb |
| Product Code: | CAB19809 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | JMJD10, MDIG, MINA, MINA53, NO52, ROX |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human RIOX2/RIOX2/MINA53 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, Mouse testis, Rat testis |
| Immunogen: | A synthesized peptide derived from human RIOX2/RIOX2/MINA53 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 84864 |
| Uniprot: | Q8IUF8 |
| Calculated MW: | 53kDa |
| Observed MW: | 53KDa |
| UniProt Protein Function: | MINA: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Belongs to the MINA53/NO66 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 3q11.2 Cellular Component: transcription factor complex; cytoplasm; nucleolus; cytosol; nucleus Molecular Function:dioxygenase activity; metal ion binding Biological Process: transcription, DNA-dependent; ribosome biogenesis and assembly; negative regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008] |
| UniProt Code: | Q8IUF8 |
| NCBI GenInfo Identifier: | 74750624 |
| NCBI Gene ID: | 84864 |
| NCBI Accession: | Q8IUF8.1 |
| UniProt Related Accession: | Q8IUF8 |
| Molecular Weight: | |
| NCBI Full Name: | Ribosomal oxygenase 2 |
| NCBI Synonym Full Names: | ribosomal oxygenase 2 |
| NCBI Official Symbol: | RIOX2 |
| NCBI Official Synonym Symbols: | ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
| NCBI Protein Information: | ribosomal oxygenase 2 |
| UniProt Protein Name: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA |
| UniProt Synonym Protein Names: | 60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX |
| Protein Family: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase |
| UniProt Gene Name: | MINA |
| UniProt Entry Name: | MINA_HUMAN |