Developmental Biology

Anti-RIMS2 Antibody (CAB14990)

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SKU:
CAB14990
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-RIMS2 Antibody
Antibody SKU:CAB14990
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:Jurkat, LO2, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RIMS2 (NP_055492.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MQFE TLRQ VCNS VLSH FHGV FSSP PNIL QNEL FGQT LNNA RKRS PSVS RDQN RRYD QREE REEY SQYA TSDT AMPR SPSD YADR RSQH EPQF YEDS DHLS YRDS NRRS HRHS KEYI VDDE DVES RDEY ERQR REEE YQSR YRSD PNLA RYPV KPQP YEEQ MRIH AEVS RARH ERRH SDVS LANA DLED SRIS MLRM DRPS RQRS ISER RAAM ENQR SYSM ERTR EAQG PSSY AQRT TNHS PPTP RRSP LPID RPDL RRTD SLRK QHHL DPSS AVRK TKRE KMET MLRN DSLS SDQS ESVR PPPP KPHK SKKG GKMR QISL SSSE EELA STPE YTSC DDVE IESE SVSE KG
Gene ID:9699
Uniprot:Q9UQ26
Cellular Location:Cell junction, Cell membrane, Peripheral membrane protein, presynaptic cell membrane, synapse
Calculated MW:85kDa/165kDa
Observed MW:165kDa
Synonyms:RIMS2, OBOE, RAB3IP3, RIM2
Background:The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis.
UniProt Code:Q9UQ26
NCBI GenInfo Identifier:41019522
NCBI Gene ID:9699
NCBI Accession:Q9UQ26.2
UniProt Secondary Accession:Q9UQ26,O43413, Q86XL9, Q8IWV9, Q8IWW1, B3KX91, F8WD47
UniProt Related Accession:Q9UQ26
Molecular Weight:1411
NCBI Full Name:Regulating synaptic membrane exocytosis protein 2
NCBI Synonym Full Names:regulating synaptic membrane exocytosis 2
NCBI Official Symbol:RIMS2  
NCBI Official Synonym Symbols:OBOE; RIM2; RAB3IP3  
NCBI Protein Information:regulating synaptic membrane exocytosis protein 2; RIM 2; nuclear protein; Rab3-interacting protein; RAB3 interacting protein 3; rab-3-interacting protein 3; rab3-interacting molecule 2; rab-3-interacting molecule 2; non-small cell lung cancer RimL3a prot
UniProt Protein Name:Regulating synaptic membrane exocytosis protein 2
UniProt Synonym Protein Names:Rab-3-interacting molecule 2; RIM 2; Rab-3-interacting protein 3
Protein Family:Mitochondrial carrier protein
UniProt Gene Name:RIMS2  
UniProt Entry Name:RIMS2_HUMAN
Anti-RIMS2 Antibody (CAB14990)Western blot analysis of extracts of various cell lines, using RIMS2 antibody (CAB14990) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
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