Anti-RBFOX2 Antibody (CAB20810)
- SKU:
- CAB20810
- Product Type:
- Antibody
- Antibody Type:
- Secondary Antibody
- Host Species:
- Mouse
- Isotype:
- IgG
Description
| Antibody Name: | Anti-RBFOX2 Antibody (CAB20810) |
| Antibody SKU: | CAB20810 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RBFOX2 (NP_001026865.1). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, LO2, HeLa |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human RBFOX2 (NP_001026865.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEKK KMVT QGNQ EPTT TPDA MVQP FTTI PFPP PPQN GIPT EYGV PHTQ DYAG QTGE HNLT LYGS TQAH GEQS SNSP STQN GSLT TEGG AQTD GQQS QTQS SENS ESKS TP |
| Cellular Location: | |
| Calculated MW: | 41kDa |
| Observed MW: | 50KDa/60KDa |
| Synonyms: | RTA, fxh, FOX2, RBM9, Fox-2, HNRBP2, HRNBP2, dJ106I20.3 |
| Background: | This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. |
 | Western blot analysis of extracts of various cell lines, using RBFOX2 antibody at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s. |
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