Cell Biology Antibodies 17
Anti-RASIP1 Antibody (CAB18466)
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- SKU:
- CAB18466
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-RASIP1 Antibody |
| Antibody SKU: | CAB18466 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human RASIP1. |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse skeletal muscle |
| Immunogen: | Recombinant protein of human RASIP1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 54922 |
| Uniprot: | Q5U651 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 103kDa |
 | Western blot - RASIP1 Rabbit pAb (CAB18466) |
| Synonyms: | RAIN, RASIP1 |
| Background: |
| UniProt Protein Function: | RASIP1: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; GAPs; GAPs, Ras Chromosomal Location of Human Ortholog: 19q13.33 Biological Process: angiogenesis; branching morphogenesis of a tube; negative regulation of autophagy; regulation of GTPase activity; vasculogenesis |
| UniProt Code: | Q5U651 |
| NCBI GenInfo Identifier: | 74736209 |
| NCBI Gene ID: | 54922 |
| NCBI Accession: | Q5U651.1 |
| UniProt Secondary Accession: | Q5U651,Q6U676, |
| UniProt Related Accession: | Q5U651 |
| Molecular Weight: | 103,457 Da |
| NCBI Full Name: | Ras-interacting protein 1 |
| NCBI Synonym Full Names: | Ras interacting protein 1 |
| NCBI Official Symbol: | RASIP1 |
| NCBI Official Synonym Symbols: | RAIN |
| NCBI Protein Information: | ras-interacting protein 1 |
| UniProt Protein Name: | Ras-interacting protein 1 |
| Protein Family: | Ras-interacting protein |
| UniProt Gene Name: | RASIP1 |
| UniProt Entry Name: | RAIN_HUMAN |
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