Cell Biology Antibodies 14

Anti-RALGDS Antibody (CAB17963)

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SKU:
CAB17963
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-RALGDS Antibody
Antibody SKU:CAB17963
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human RALGDS.
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, Mouse ovary, Mouse lung
Immunogen:Recombinant protein of human RALGDS.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5900
Uniprot:Q12967
Cellular Location:
Calculated MW:
Observed MW:110kDa
Anti-RALGDS Antibody (CAB17963)Western blot - RALGDS Rabbit pAb (CAB17963)
Synonyms:RGDS, RGF, RalGEF, RALGDS
Background:Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010]
UniProt Protein Function:RALGDS: Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GEFs, Ras; GEFs

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: brush border; cytosol; nucleus

Molecular Function:GTPase regulator activity; protein binding

Biological Process: Ras protein signal transduction

NCBI Summary:Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010]
UniProt Code:Q12967
NCBI GenInfo Identifier:14549162
NCBI Gene ID:5900
NCBI Accession:Q12967.2
UniProt Secondary Accession:Q12967,Q5T7V4, Q6KH11, Q6PCE1, Q6ZSD5, Q9HAX7, Q9HAY1 Q9HCT1, Q9P2N8, B7Z753, E7ER93, E7ERZ0,
UniProt Related Accession:Q12967
Molecular Weight:99,325 Da
NCBI Full Name:Ral guanine nucleotide dissociation stimulator
NCBI Synonym Full Names:ral guanine nucleotide dissociation stimulator
NCBI Official Symbol:RALGDS  
NCBI Official Synonym Symbols:RGF; RGDS; RalGEF  
NCBI Protein Information:ral guanine nucleotide dissociation stimulator
UniProt Protein Name:Ral guanine nucleotide dissociation stimulator
UniProt Synonym Protein Names:Ral guanine nucleotide exchange factor; RalGEF
Protein Family:Ral guanine nucleotide dissociation stimulator
UniProt Gene Name:RALGDS  
UniProt Entry Name:GNDS_HUMAN
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