Cell Biology Antibodies 11

Rac1/2/3 Rabbit Polyclonal Antibody (CAB7720)

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SKU:
CAB7720
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
MIG5, MRD48, Rac-1, TC-25, p21-Rac1, Rac1/2/3
Research Use:
Cell Biology
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Description

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Rac1/2/3 Antibody (CAB7720)

The Rac1/2/3 Antibody (CAB7720) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RAC1 protein, it enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology, cancer research, and drug development.RAC1 plays a critical role in cellular processes such as cell migration, proliferation, and survival, making it a key player in diverse biological functions. Dysregulation of RAC1 signaling has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Rac1/2/3 Antibody
SKU:CAB7720
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MQAI KCVV VGDG AVGK TCLL ISYT TNAF PGEY IPTV FDNY SANV MVDG KPVN LGLW DTAG QEDY DRLR PLSY PQTD VFLI CFSL VSPA SFEN VRAK WYPE VRHH CPNT PIIL VGTK LDLR DDKD TIEK LKEK KLTP ITYP QGLA MAKE IGAV KYLE CSAL TQRG LKTV FDEA IRAV LCPP PVKK RKRK CLLL
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MIG5, MRD48, Rac-1, TC-25, p21-Rac1, Rac1/2/3
Positive Sample:A-431, Mouse brain, Rat brain, Rat spleen
Cellular Localization:Cell Membrane, Cytoplasm, Cytoplasmic Side, Lipid-Anchor, Melanosome, Nucleus.
Calculated MW:21kDa
Observed MW:21kDa

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID5879 5880 5881
RRIDAB_2771932
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Rac1/2/3 Rabbit pAb (CAB7720) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageWestern blot analysis of lysates from A-431 cells, using Rac1/2/3 Rabbit pAb (CAB7720) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunofluorescence analysis of C6 cells using Rac1/2/3 Rabbit pAb (CAB7720) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of NIH-3T3 cells using Rac1/2/3 Rabbit pAb (CAB7720) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using Rac1/2/3 Rabbit pAb (CAB7720) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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