Anti-RAB1A Antibody [4G10]
- SKU:
- STMA00218
- Antibody Type:
- Monoclonal
- Applications:
- WB
- Applications:
- IP
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Mouse
- Isotype:
- IgG1
Description
RAB1A Antibody [4G10]
RAB1A Antibody [4G10] is a mouse monoclonal antibody directed against RAB1A, offered by Assay Genie for research applications. Reported applications include WB and IP. Reported reactivity: Human and Mouse. Supplied as IgG1, purified by Protein G.
RAB1A is a small GTPase localized to the membranes of the endoplasmic reticulum (ER) and Golgi apparatus. It regulates vesicular trafficking between these compartments and is essential for maintaining cellular homeostasis. In the nervous system, RAB1A supports the transport of proteins critical for synaptic function and neuronal survival. It has been implicated in the regulation of growth hormone secretion and intracellular signaling pathways. Dysfunction of RAB1A-mediated trafficking contributes to ER stress and impaired proteostasis—key features of neurodegenerative diseases such as Parkinson’s and Alzheimer’s. As a regulator of early secretory pathways, RAB1A is a potential target for modulating protein misfolding and aggregation in neurodegeneration. This antibody is also available conjugated to ATTO 390, ATTO 488, ATTO 594, APC, Biotin, FITC, HRP, PerCP and RPE. Supplied in 100 µg. For research use only; not for diagnostic or therapeutic procedures.
| Product Name: | RAB1A Antibody [4G10] |
| Product SKU: | STMA00218 |
| Size: | 100 µg |
| Target: | RAB1A |
| Host Species: | Mouse |
| Antibody Type: | Monoclonal |
| Clone ID: | 4G10 |
| Research Areas: | Cancer, Cell Signaling, Cell Signaling, Autophagy, Golgi Proteins, Alzheimer's Disease, Growth Factors, Membrane Trafficking Proteins, Neurodegeneration, Neuroscience, Parkinson's Disease, Protein Trafficking |
| Buffer: | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Storage & Shipping: | Store at -20°C. Shipped on Blue Ice or 4°C. Conjugated variants should be stored according to the product label. |
| Format: | Liquid |
| Applications: | WB, IP |
| Antibody Isotype: | IgG1 |
| Purification: | Protein G Purified |
| Concentration: | 1mg/ml |
| Reactivity: | Human, Mouse |
| Recommended Dilution: | WB (1:1000); optimal dilutions for assays should be determined by the user. |
| Specificity: | Detects ~23 kDa. Cross-reacts with RAB1B and RAB1C. |
| Guarantee: | 12 months from date of dispatch |
| Immunogen: | Full length recombinant Human RAB1A protein |
| Immunogen Species: | Human |
| Accession Number: | NP_004152.1 |
| Gene ID: | 5861 |
| Swiss-Prot: | P62820 |
| Cellular Localization: | Cytoplasm | Endoplasmic reticulum | Endosome | Golgi apparatus | Membrane |
| Tissue Specificity: | Low tissue specificity. |
| Alternative Names: | GTP binding protein RAB 1A, RAB 1, Rab 1A, Rab1A, RAB1A member RAS oncogene family, RAB1A_HUMAN, Ras related protein Rab 1A, Ras-related protein Rab-1A, YPT1-related protein, RAB1 |
| References: | 1. Yang, X. et al. (2016) Oncogene. 35(44):5699-5704 2. pubchem.ncbi.nlm.nih.gov/protein/P62820 |
| Note: | For research use only. |
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