Name: Anti-PXDN Antibody (CAB17929)
Brand: Cell Biology Antibodies 15
SKU: CAB17929
Availability: OutOfStock

Antibody Name:	Anti-PXDN Antibody
Antibody SKU:	CAB17929
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant protein of human PXDN.

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	Raji, Mouse lung

Immunogen:	Recombinant protein of human PXDN.
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	7837
Uniprot:	Q92626
Cellular Location:
Calculated MW:
Observed MW:	165KDa

Western blot - PXDN Rabbit pAb (CAB17929)

Synonyms:	PXN, VPO, MG50, PRG2, ASGD7, COPOA, D2S448, D2S448E, PXDN
Background:	This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.

UniProt Protein Function:	PXDN: Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. Belongs to the peroxidase family. XPO subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:EC 1.11.1.7; Oxidoreductase; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2p25.3 Cellular Component: endoplasmic reticulum; extracellular matrix; extracellular region; extracellular space; proteinaceous extracellular matrix Molecular Function:extracellular matrix structural constituent; heme binding; interleukin-1 receptor antagonist activity; metal ion binding; peroxidase activity Biological Process: extracellular matrix organization; hydrogen peroxide catabolic process; immune response; negative regulation of cytokine and chemokine mediated signaling pathway; response to oxidative stress Disease: Corneal Opacification With Other Ocular Anomalies
NCBI Summary:	This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014]
UniProt Code:	Q92626
NCBI GenInfo Identifier:	109150416
NCBI Gene ID:	7837
NCBI Accession:	NP_036425.1
UniProt Secondary Accession:	Q92626,Q4KMG2, A8QM65, D6W4Y0,
UniProt Related Accession:	Q92626
Molecular Weight:
NCBI Full Name:	peroxidasin homolog
NCBI Synonym Full Names:	peroxidasin
NCBI Official Symbol:	PXDN
NCBI Official Synonym Symbols:	PXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E
NCBI Protein Information:	peroxidasin homolog
UniProt Protein Name:	Peroxidasin homolog
UniProt Synonym Protein Names:	Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 protein
UniProt Gene Name:	PXDN