KO Validated Antibodies 2

Anti-PSIP1 Antibody (CAB18101)[KO Validated]

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SKU:
CAB18101
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-PSIP1 Antibody [KO Validated]
Antibody SKU:CAB18101
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NMLK GQHE KEAA DRKR KQEE QMET EQQN KDEG KKPE VKKV EKKR ETSM DSRL QRIH AEIK NSLK IDNL DVNR CIEA LDEL ASLQ VTMQ QAQK HTEM ITTL KKIR RFKV SQVI MEKS TMLY NKFK NMFL VGEG DSVI TQVL NKSL AEQR QHEE ANKT KDQG KKGP NKKL EKEQ TGSK TLNG GSDA QDGN QPQH NGES NEDS KDNH EAST KKKP SSEE RETE ISLK DSTL DN
Gene ID:11168
Uniprot:O75475
Cellular Location:Nucleus
Calculated MW:37kDa/60kDa
Observed MW:75kDa
Anti-PSIP1 Antibody [KO Validated] (CAB18101)Western blot analysis of extracts from normal (control) and PSIP1 knockout (KO) 293T cells, using PSIP1 antibody (CAB18101) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
Synonyms:PSIP1, DFS70, LEDGF, PAIP, PSIP2, p52, p75
Background:
UniProt Protein Function:Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
UniProt Code:O75475
NCBI GenInfo Identifier:68565853
NCBI Gene ID:11168
NCBI Accession:O75475.1
UniProt Secondary Accession:O75475,O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6 D3DRI9,
UniProt Related Accession:O75475
Molecular Weight:76; 51; 45 kDa
NCBI Full Name:PC4 and SFRS1-interacting protein
NCBI Synonym Full Names:PC4 and SFRS1 interacting protein 1
NCBI Official Symbol:PSIP1  
NCBI Official Synonym Symbols:p52; p75; PAIP; DFS70; LEDGF; PSIP2  
NCBI Protein Information:PC4 and SFRS1-interacting protein
UniProt Protein Name:PC4 and SFRS1-interacting protein
UniProt Synonym Protein Names:CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; Transcriptional coactivator p75/p52
Protein Family:PC4 and SFRS1-interacting protein
UniProt Gene Name:PSIP1  
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