Epigenetics & Nuclear Signaling Antibodies 4
Anti-Protein BTG2 Antibody (CAB9848)
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- SKU:
- CAB9848
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-Protein BTG2 Antibody |
| Antibody SKU: | CAB9848 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human BTG2 (NP_006754.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, LO2, HT-1080, BT-474 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human BTG2 (NP_006754.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSHG KGTD MLPE IAAA VGFL SSLL RTRG CVSE QRLK VFSG ALQE ALTE HYKH HWFP EKPS KGSG YRCI RINH KMDP IISR VASQ IGLS QPQL HQLL PSEL TLWV DPYE VSYR IGED GSIC VLYE EAPL AASC GLLT CKNQ VLLG RSSP SKNY VMAV SS |
| Gene ID: | 7832 |
| Uniprot: | P78543 |
| Cellular Location: | |
| Calculated MW: | 17kDa |
| Observed MW: | 17kDa |
| Synonyms: | BTG2, APRO1, PC3, TIS21 |
| Background: | The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. |
| UniProt Protein Function: | BTG2: Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors. Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. Belongs to the BTG family. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 1q32 Molecular Function:protein binding Biological Process: response to peptide hormone stimulus; dentate gyrus development; transcription, DNA-dependent; protein amino acid methylation; DNA repair; response to organic cyclic substance; anterior/posterior pattern formation; negative regulation of cell proliferation; response to mechanical stimulus; negative regulation of translation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; response to electrical stimulus; response to DNA damage stimulus; neurite development; associative learning; central nervous system neuron development |
| NCBI Summary: | The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P78543 |
| NCBI GenInfo Identifier: | 5802988 |
| NCBI Gene ID: | 7832 |
| NCBI Accession: | NP_006754.1 |
| UniProt Secondary Accession: | P78543,Q3KR25, Q5VUT0, A0A024R986, |
| UniProt Related Accession: | P78543 |
| Molecular Weight: | 17,416 Da |
| NCBI Full Name: | protein BTG2 |
| NCBI Synonym Full Names: | BTG family, member 2 |
| NCBI Official Symbol: | BTG2 |
| NCBI Official Synonym Symbols: | PC3; TIS21 |
| NCBI Protein Information: | protein BTG2; pheochromacytoma cell-3; B-cell translocation gene 2; NGF-inducible anti-proliferative protein PC3; nerve growth factor-inducible anti-proliferative |
| UniProt Protein Name: | Protein BTG2 |
| UniProt Synonym Protein Names: | BTG family member 2; NGF-inducible anti-proliferative protein PC3 |
| Protein Family: | Protein |
| UniProt Gene Name: | BTG2 |
| UniProt Entry Name: | BTG2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BTG2 antibody (CAB9848) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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