Cell Biology Antibodies 3

Anti-PPP1R7 Antibody (CAB13041)

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SKU:
CAB13041
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PPP1R7 Antibody
Antibody SKU:CAB13041
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_002703.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:293T, SGC-7901, Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_002703.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IASN RIKK IENI SHLT ELQE FWMN DNLL ESWS DLDE LKGA RSLE TVYL ERNP LQKD PQYR RKVM LALP SVRQ IDAT FVRF
Gene ID:5510
Uniprot:Q15435
Cellular Location:Nucleus
Calculated MW:25kDa/27kDa/32kDa/36kDa/41kDa
Observed MW:39kDa
Synonyms:PPP1R7, SDS22
Background:This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:PPP1R7: Regulatory subunit of protein phosphatase 1. Belongs to the SDS22 family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: chromosome; cytoplasm; nucleus

Molecular Function:protein binding; protein phosphatase type 1 regulator activity

Biological Process: positive regulation of protein amino acid dephosphorylation

NCBI Summary:This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Code:Q15435
NCBI GenInfo Identifier:74762145
NCBI Gene ID:5510
NCBI Accession:Q15435.1
UniProt Secondary Accession:Q15435,Q9UQE5, Q9UQE6, Q9Y6K4, B4DFD4, B5MCY6,
UniProt Related Accession:Q15435
Molecular Weight:25,593 Da
NCBI Full Name:Protein phosphatase 1 regulatory subunit 7
NCBI Synonym Full Names:protein phosphatase 1 regulatory subunit 7
NCBI Official Symbol:PPP1R7  
NCBI Official Synonym Symbols:SDS22  
NCBI Protein Information:protein phosphatase 1 regulatory subunit 7
UniProt Protein Name:Protein phosphatase 1 regulatory subunit 7
UniProt Synonym Protein Names:Protein phosphatase 1 regulatory subunit 22
Protein Family:Protein phosphatase 1 regulatory
UniProt Gene Name:PPP1R7  
UniProt Entry Name:PP1R7_HUMAN
Anti-PPP1R7 Antibody (CAB13041)Western blot analysis of extracts of various cell lines, using PPP1R7 antibody (CAB13041) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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