Metabolism Antibodies 2
Anti-PNLIP Antibody (CAB6396)
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- SKU:
- CAB6396
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-PNLIP Antibody |
| Antibody SKU: | CAB6396 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human PNLIP (NP_000927.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse pancreas |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human PNLIP (NP_000927.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IGHS LGAH AAGE AGRR TNGT IGRI TGLD PAEP CFQG TPEL VRLD PSDA KFVD VIHT DGAP IVPN LGFG MSQV VGHL DFFP NGGV EMPG CKKN ILSQ IVDI DGIW EGTR DFAA CNHL RSYK YYTD SIVN PDGF AGFP CASY NVFT ANKC FPCP SGGC PQMG HYAD RYPG KTND VGQK FYLD TGDA SNFA RWRY KVSV TLSG KKVT GHIL VSLF GNKG NSKQ YEIF KGTL KPDS THSN EFDS DVDV GDLQ MVKF IWYN NVIN PTLP RVGA SKII VETN VGKQ FNFC SPET VREE VLLT LTPC |
| Gene ID: | 5406 |
| Uniprot: | P16233 |
| Cellular Location: | Secreted |
| Calculated MW: | 51kDa |
| Observed MW: | 55kDa |
| Synonyms: | PNLIP, PL, PNLIPD, PTL |
| Background: | This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. |
| UniProt Protein Function: | PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.1.1.3; Lipid Metabolism - glycerolipid; Hydrolase; Secreted Chromosomal Location of Human Ortholog: 10q26.1 Cellular Component: extracellular region Molecular Function:triacylglycerol lipase activity; metal ion binding Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process Disease: Pancreatic Lipase Deficiency |
| NCBI Summary: | This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P16233 |
| NCBI GenInfo Identifier: | 126318 |
| NCBI Gene ID: | 5406 |
| NCBI Accession: | P16233.1 |
| UniProt Secondary Accession: | P16233,Q5VSQ2, |
| UniProt Related Accession: | P16233 |
| Molecular Weight: | 51,157 Da |
| NCBI Full Name: | Pancreatic triacylglycerol lipase |
| NCBI Synonym Full Names: | pancreatic lipase |
| NCBI Official Symbol: | PNLIP |
| NCBI Official Synonym Symbols: | PL; PTL; PNLIPD |
| NCBI Protein Information: | pancreatic triacylglycerol lipase; triacylglycerol acylhydrolase |
| UniProt Protein Name: | Pancreatic triacylglycerol lipase |
| Protein Family: | Plexin |
| UniProt Gene Name: | PNLIP |
| UniProt Entry Name: | LIPP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PNLIP antibody (CAB6396) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using PNLIP antibody (CAB6396) at dilution of 1:200 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using PNLIP antibody (CAB6396). Blue: DAPI for nuclear staining. |
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