Metabolism Antibodies 2
Anti-PISD Antibody (CAB4580)
- SKU:
- CAB4580
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PISD
- Synonyms:
- DJ858B16
- Synonyms:
- PSD
- Synonyms:
- PSDC
- Synonyms:
- PSSC
- Synonyms:
- dJ858B16.2
- Research Area:
- Metabolism
Description
| Product Name: | PISD Rabbit pAb |
| Product Code: | CAB4580 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | PISD, DJ858B16, PSD, PSDC, PSSC, dJ858B16.2 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human PISD (NP_055153.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-375 of human PISD (NP_055153.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MMCQ SEAR QGPE LRAA KWLH FPQL ALRR RLGQ LSCM SRPA LKLR SWPL TVLY YLLP FGAL RPLS RVGW RPVS RVAL YKSV PTRL LSRA WGRL NQVE LPHW LRRP VYSL YIWT FGVN MKEA AVED LHHY RNLS EFFR RKLK PQAR PVCG LHSV ISPS DGRI LNFG QVKN CEVE QVKG VTYS LESF LGPR MCTE DLPF PPAA SCDS FKNQ LVTR EGNE LYHC VIYL APGD YHCF HSPT DWTV SHRR HFPG SLMS VNPG MARW IKEL FCHN ERVV LTGD WKHG FFSL TAVG ATNV GSIR IYFD RDLH TNSP RHSK GSYN DFSF VTHT NREG VPMR KGEH LGEF NLGS TIVL IFEA PKDF NFQL KTGQ KIRF GEAL GSL |
| Gene ID: | 23761 |
| Uniprot: | Q9UG56 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 43kDa/46kDa |
| Observed MW: | 50kDa |
| UniProt Protein Function: | PISD: Belongs to the phosphatidylserine decarboxylase family. Heterodimer. 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum; Lipid Metabolism - glycerophospholipid; Lyase; EC 4.1.1.65 Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: mitochondrion; nucleus Molecular Function:phosphatidylserine decarboxylase activity Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process |
| NCBI Summary: | Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]).[supplied by OMIM, Jul 2010] |
| UniProt Code: | Q9UG56 |
| NCBI GenInfo Identifier: | 311033492 |
| NCBI Gene ID: | 23761 |
| NCBI Accession: | Q9UG56.4 |
| UniProt Secondary Accession: | Q9UG56,O43207, O95535, Q6IC28, Q96GQ2, Q9UGA9, B1AKM7 |
| UniProt Related Accession: | Q9UG56 |
| Molecular Weight: | 409 |
| NCBI Full Name: | Phosphatidylserine decarboxylase proenzyme |
| NCBI Synonym Full Names: | phosphatidylserine decarboxylase |
| NCBI Official Symbol: | PISD |
| NCBI Official Synonym Symbols: | PSD; PSDC; PSSC; DJ858B16; dJ858B16.2 |
| NCBI Protein Information: | phosphatidylserine decarboxylase proenzyme |
| UniProt Protein Name: | Phosphatidylserine decarboxylase proenzyme |
| UniProt Gene Name: | PISD |
| UniProt Entry Name: | PISD_HUMAN |
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