Cell Biology Antibodies 14

Phospho-Tau-Ser416 Rabbit Polyclonal Antibody (CABP1101)

(No reviews yet) Write a Review
SKU:
CABP1101
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103, Tau-PHF6, Phospho-Tau-Ser416
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Phospho-Tau-Ser416 Antibody (CABP1101)

The Phospho-Tau-Ser416 Antibody (CABP1101) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, specifically designed for detecting phosphorylation at serine 416 on tau, is highly reactive with human samples and has been validated for use in Western blot applications.Tau protein is commonly associated with neurodegenerative disorders such as Alzheimer's disease, where abnormal phosphorylation leads to the formation of tau tangles in the brain. The Phospho-Tau (Ser416) antibody allows for the detection and analysis of phosphorylated tau in different cell types, providing insights into the role of tau phosphorylation in neurodegeneration.

This antibody is validated for use in WB, IHC-P, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Phospho-Tau-Ser416 Antibody
SKU:CABP1101
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:TGSI D
Tested Applications:WB IHC-P ELISA IF-P
Recommended Dilution:
WB1:500 - 1:2000
IF-P1:50 - 1:200
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103, Tau-PHF6, Phospho-Tau-Ser416
Positive Sample:NIH/3T3
Cellular Localization:Cell Membrane, Cell Projection, Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Axon, Cytoskeleton, Cytosol.
Calculated MW:79kDa
Observed MW:95kDa

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Purification MethodAffinity purification
Gene ID4137
RRIDAB_2863970
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from NIH/3T3 cells, using Phospho-Tau-Ser416 Rabbit pAb (CAB0002). NIH/3T3 cells were treated by CIP(20uL/400ul) at 37℃ for 1 hour. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human brain using Phospho-Tau-Ser416 Rabbit pAb (CABP1101) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of paraffin-embedded Mouse brain using Phospho-Tau-Ser416 Rabbit pAb (CABP1101) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products