Cell Death Antibodies 2

Phospho-PKC delta-Y311 Rabbit Polyclonal Antibody (CABP0496)

(No reviews yet) Write a Review
SKU:
CABP0496
Product Type:
Antibody
Applications:
WB
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Death
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
MAY1, PKCD, ALPS3, CVID9, nPKC-delta, Phospho-PKC delta-Y311
Research Use:
Cell Death
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Phospho-PKC delta-Y311 Antibody (CABP0496)

The Phospho-PKC delta-Y311 Antibody (CABP0496) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications.PKCdelta is a member of the protein kinase C (PKC) family, known for its involvement in signaling pathways regulating cell proliferation, differentiation, and apoptosis. Phosphorylation of PKCdelta at tyrosine 311 has been linked to its activation and downstream signaling cascades, making it a valuable target for studies in cancer biology, cell signaling, and drug development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Phospho-PKC delta-Y311 Antibody
SKU:CABP0496
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:VGIY Q
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:MAY1, PKCD, ALPS3, CVID9, nPKC-delta, Phospho-PKC delta-Y311
Positive Sample:U-937 treated with PMA, RAW 264.7 treated with PMA
Cellular Localization:Cell Membrane, Cytoplasm, Endoplasmic Reticulum, Mitochondrion, Nucleus, Peripheral Membrane Protein, Perinuclear Region.
Calculated MW:78kDa
Observed MW:78kDa

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome.

Purification MethodAffinity purification
Gene ID5580
RRIDAB_2771424
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from U937 and Raw264.7 cells, using Phospho-PKC delta-Y311 Rabbit pAb (CABP0496) at 1:1000 dilution. U-937 cells were treated with PMA/TPA (200nM) for 30 minutes.RAW 264.7 cells were treated with PMA (200 nM) for 30 minutes . Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products