Cell Biology Antibodies 15

Anti-Phospho-Erk1/2-T202/Y204 Antibody (CABP1120)

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SKU:
CABP1120
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-Phospho-Erk1/2-T202/Y204 Antibody
Antibody SKU:CABP1120
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A phospho specific peptide corresponding to residues surrounding T202/Y204 of human Erk1/2.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:A phospho specific peptide corresponding to residues surrounding T202/Y204 of human Erk1/2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5594/ 5595
Uniprot:P28482/P2736
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Anti-Phospho-Erk1/2-T202/Y204 Antibody (CABP1120)Western blot - Phospho-Erk1/2-T202/Y204 Rabbit pAb (CABP1120)
Synonyms:
Background:This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
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