Cell Biology Antibodies 15

Phospho-PSD93/chapsyn-110/DLG2-Y340 Rabbit Polyclonal Antibody (CABP1080)

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SKU:
CABP1080
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
PSD93, PSD-93, PPP1R58, chapsyn-110, Phospho-PSD93/chapsyn-110/DLG2-Y340
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Description

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Phospho-PSD93/chapsyn-110/DLG2-Y340 Antibody (CABP1080)

The Phospho-PSD93/chapsyn-110/DLG2-Y340 Antibody (CABP1080) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific for phosphorylated DLG2 at tyrosine 340 and is validated for use in various applications, including Western blot and immunohistochemistry.DLG2, also known as PSD-93, is a scaffold protein that interacts with NMDA receptors and other synaptic proteins to regulate synaptic transmission and plasticity. Phosphorylation of DLG2 at tyrosine 340 has been linked to changes in synaptic strength and neuronal activity, making it essential for understanding the molecular mechanisms underlying learning and memory.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Phospho-PSD93/chapsyn-110/DLG2-Y340 Antibody
SKU:CABP1080
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:DDYT R
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PSD93, PSD-93, PPP1R58, chapsyn-110, Phospho-PSD93/chapsyn-110/DLG2-Y340
Positive Sample:293T treated with ATP, NIH/3T3 treated with ATP, C6 treated with ATP
Cellular Localization:Axon Cytoplasm, Basolateral Plasma Membrane, Cytosol, Neuromuscular Junction, Neuron Projection, Perikaryon, Plasma Membrane, Postsynaptic Density, Postsynaptic Density Membrane.
Calculated MW:98kDa
Observed MW:105kDa

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.

Purification MethodAffinity purification
Gene ID1740
RRIDAB_2863952
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Phospho-PSD93/chapsyn-110/DLG2-Y340 Rabbit pAb (CABP1080) at 1:1000 dilution. 293T cells were treated with ATP(5 mM) at 30℃ for 1 hour. NIH/3T3 cells were treated with ATP(5 mM) at 30℃ for 1 hour. C6 cells were treated with ATP(5 mM) at 30℃ for 1 hour. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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