Cell Biology Antibodies 14

Phospho-DDR1-Y792 Rabbit Polyclonal Antibody (CABP1072)

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SKU:
CABP1072
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A, Phospho-DDR1-Y792
Research Use:
Cell Biology
Frequently bought together:

Description

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Phospho-DDR1-Y792 Antibody (CABP1072)

The Phospho-DDR1-Y792 Antibody (CABP1072) is a high-quality antibody developed for reliable detection and analysis of target proteins. DDR1 is a receptor tyrosine kinase that plays a crucial role in cell adhesion, migration, and proliferation, making it a key player in cancer progression and metastasis.This antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the phosphorylated form of DDR1 at tyrosine 792, researchers can accurately detect and analyze DDR1 activation in various cell types, providing valuable insights into its role in cancer biology.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Phospho-DDR1-Y792 Antibody
SKU:CABP1072
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:NLYA G
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A, Phospho-DDR1-Y792
Positive Sample:293T treated with ATP, NIH/3T3 treated with ATP, C6 treated with ATP
Cellular Localization:Cell Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:101kDa
Observed MW:125kDa

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification MethodAffinity purification
Gene ID780
RRIDAB_2863944
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Phospho-DDR1-Y792 Rabbit pAb (CABP1072) at 1:1000 dilution. 293T cells were treated with ATP(5 mM) at 30℃ for 1 hour. NIH/3T3 cells were treated with ATP(5 mM) at 30℃ for 1 hour. C6 cells were treated with ATP(5 mM) at 30℃ for 1 hour. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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