Anti-Periostin Antibody (CAB9009)
- SKU:
- CAB9009
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- OSF-2
- Synonyms:
- OSF2
- Synonyms:
- PDLPOSTN
- Synonyms:
- PN
- Research Area:
- Cell Biology
Description
| Product Name: | Periostin Rabbit mAb |
| Product Code: | CAB9009 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | OSF-2, OSF2, PDLPOSTN, PN |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Periostin |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | MCF7 |
| Immunogen: | A synthesized peptide derived from human Periostin |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10631 |
| Uniprot: | Q15063 |
| Calculated MW: | 85kDa |
| Observed MW: | 80KDa |
| UniProt Protein Function: | POSTN: Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 13q13.3 Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; trans-Golgi network Molecular Function:heparin binding; protein binding; cell adhesion molecule binding Biological Process: tissue development; extracellular matrix organization and biogenesis; regulation of Notch signaling pathway; cell adhesion; skeletal development |
| NCBI Summary: | This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015] |
| UniProt Code: | Q15063 |
| NCBI GenInfo Identifier: | 93138709 |
| NCBI Gene ID: | 10631 |
| NCBI Accession: | Q15063.2 |
| UniProt Secondary Accession: | Q15063,Q15064, Q29XZ0, Q3KPJ5, Q5VSY5, Q8IZF9, B1ALD8 C0IMJ1, C0IMJ2, C0IMJ4, D2KRH7, F5H628, |
| UniProt Related Accession: | Q15063 |
| Molecular Weight: | 80,357 Da |
| NCBI Full Name: | Periostin |
| NCBI Synonym Full Names: | periostin, osteoblast specific factor |
| NCBI Official Symbol: | POSTN |
| NCBI Official Synonym Symbols: | PN; OSF2; OSF-2; PDLPOSTN; periostin |
| NCBI Protein Information: | periostin; periodontal ligament-specific periostin; osteoblast specific factor 2 (fasciclin I-like) |
| UniProt Protein Name: | Periostin |
| UniProt Synonym Protein Names: | Osteoblast-specific factor 2; OSF-2 |
| Protein Family: | Periostin |
| UniProt Gene Name: | POSTN |
| UniProt Entry Name: | POSTN_HUMAN |
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