Cell Biology Antibodies 10

Anti-PENK Antibody (CAB6302)

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SKU:
CAB6302
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
PE, PENK-A, PENK
Research Use:
Cell Biology
Frequently bought together:

Description

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PENK Antibody (CAB6302)

The PENK Antibody (CAB6302) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is optimized for Western blot applications.Proenkephalin A is a key player in the endogenous opioid system, known for its role in modulating pain perception and mood. Research involving proenkephalin A has implications for understanding pain management, addiction, and mental health disorders.

This antibody is validated for use in WB, IHC-P, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PENK Antibody
SKU:CAB6302
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:ECSQ DCAT CSYR LVRP ADIN FLAC VMEC EGKL PSLK IWET CKEL LQLS KPEL PQDG TSTL RENS KPEE SHLL AKRY GGFM KRYG GFMK KMDE LYPM EPEE EANG SEIL AKRY GGFM KKDA EEDD SLAN SSDL LKEL LETG DNRE RSHH QDGS DNEE EVSK RYGG FMRG LKRS PQLE DEAK ELQK RYGG FMRR VGRP EWWM DYQK RYGG FLKR FAEA LPSD EEGE SYSK EVPE MEKR YGGF MRF
Tested Applications:WB IHC-P ELISA IF-P
Recommended Dilution:
WB1:100 - 1:500
IF-P1:50 - 1:200
IHC-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PE, PENK-A, PENK
Positive Sample:THP-1
Cellular Localization:Secreted.
Calculated MW:31kDa
Observed MW:36kDa

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities.

Purification MethodAffinity purification
Gene ID5179
RRIDAB_2766907
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from THP-1 cells, using PENK Rabbit pAb (CAB6302) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 120s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human prostate using PENK Rabbit pAb (CAB6302) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunofluorescence analysis of paraffin-embedded Human adrenal gland using PENK Rabbit pAb (CAB6302) at dilution of 1:20 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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