Anti-Parvalbumin Antibody [C12]

Parvalbumin Antibody [C12]

Parvalbumin Antibody [C12] is a mouse monoclonal antibody directed against Parvalbumin, offered by Assay Genie for research applications. Reported applications include WB, ICC/IF, ELISA and IHC. Reported reactivity: Human, Rat and Mouse. Supplied as IgG2a, purified by Protein A.

Parvalbumin is a calcium-binding protein predominantly expressed in fast-spiking GABAergic interneurons. It plays a crucial role in buffering intracellular calcium and regulating neuronal excitability and synaptic timing. Alterations in parvalbumin-expressing interneurons have been implicated in a range of neurological and psychiatric disorders, including Alzheimer’s disease, schizophrenia, autism spectrum disorders, and age-related cognitive decline. Loss of parvalbumin function disrupts inhibitory signaling, leading to network hyperexcitability and impaired cognitive processing. As a marker of interneuron health and circuit integrity, parvalbumin is a valuable target for studying neural dysfunction and developing interventions aimed at restoring excitatory-inhibitory balance in the brain. This antibody is also available conjugated to ATTO 390, ATTO 488, ATTO 594, APC, Biotin, FITC, HRP, PerCP and RPE. Supplied in 100 µg. For research use only; not for diagnostic or therapeutic procedures.