KO Validated Antibodies 1

[KO Validated] PARK7 Rabbit Polyclonal Antibody (CAB0987)

(No reviews yet) Write a Review
SKU:
CAB0987
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
Reactivity:
Human, Mouse
Synonyms:
DJ1, DJ-1, GATD2, HEL-S-67p, K7
Research Use:
Autophagy
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

[KO Validated] PARK7 Antibody (CAB0987)

The [KO Validated] PARK7 Antibody (CAB0987) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, developed using rabbits, demonstrates high reactivity with human samples and has been rigorously validated for Western blot applications. By specifically binding to the DJ-1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for use in studies focused on neurodegenerative diseases, Parkinson's disease, and other disorders associated with DJ-1 dysfunction.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:[KO Validated] PARK7 Antibody
SKU:CAB0987
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MASK RALV ILAK GAEE METV IPVD VMRR AGIK VTVA GLAG KDPV QCSR DVVI CPDA SLED AKKE GPYD VVVL PGGN LGAQ NLSE SAAV KEIL KEQE NRKG LIAA ICAG PTAL LAHE IGFG SKVT THPL AKDK MMNG GHYT YSEN RVEK DGLI LTSR GPGT SFEF ALAI VEAL NGKE VAAQ VKAP LVLK D
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DJ1, DJ-1, GATD2, HEL-S-67p, K7
Positive Sample:HeLa, NIH/3T3, Jurkat
Cellular Localization:Cell Membrane, Cytoplasm, Lipid-Anchor, Membrane Raft, Mitochondrion, Nucleus.
Calculated MW:20kDa
Observed MW:20kDa

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Purification MethodAffinity purification
Gene ID11315
RRIDAB_2757506
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] DJ-1/PARK7 Rabbit pAb (CAB0987) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product ImageWestern blot analysis of lysates from wild type (WT) and DJ-1/PARK7 knockout (KO) 293T cells, using [KO Validated] DJ-1/PARK7 Rabbit pAb (CAB0987) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
View AllClose

0 Reviews

View AllClose

Related Products