Epigenetics & Nuclear Signaling Antibodies 5
Anti-PABPN1 Antibody (CAB1735)
(No reviews yet)
Write a Review
- SKU:
- CAB1735
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Polyclonal AntibodyPN1 Rabbit Monoclonal Antibody |
| Antibody SKU: | CAB1735 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PABPN1 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, Raji, Mouse lung, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human PABPN1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8106 |
| Uniprot: | Q86U42 |
| Cellular Location: | |
| Calculated MW: | 49kDa |
| Observed MW: | 50KDa |
 | Western blot - PABPN1 Rabbit mAb (CAB1735) |
| Synonyms: | OPMD, PAB2, PABII, PABP-2, PABP2 |
| Background: | This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q86U42 |
| NCBI GenInfo Identifier: | 46403176 |
| NCBI Gene ID: | 8106 |
| NCBI Accession: | Q86U42.3 |
| UniProt Secondary Accession: | Q86U42,O43484, D3DS49, |
| UniProt Related Accession: | Q86U42 |
| Molecular Weight: | 306 |
| NCBI Full Name: | Polyadenylate-binding protein 2 |
| NCBI Synonym Full Names: | poly(A) binding protein, nuclear 1 |
| NCBI Official Symbol: | PABPN1 |
| NCBI Official Synonym Symbols: | OPMD; PAB2; PABII; PABP2; PABP-2 |
| NCBI Protein Information: | polyadenylate-binding protein 2; poly(A) binding protein 2; poly(A) binding protein II |
| UniProt Protein Name: | Polyadenylate-binding protein 2 |
| UniProt Synonym Protein Names: | Nuclear poly(A)-binding protein 1; Poly(A)-binding protein II; PABII; Polyadenylate-binding nuclear protein 1 |
| UniProt Gene Name: | PABPN1 |
| UniProt Entry Name: | PABP2_HUMAN |
Related Products
