Cell Biology Antibodies 16

Anti-PABPC5 Antibody (CAB9997)

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SKU:
CAB9997
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-PABPC5 Antibody
Antibody SKU:CAB9997
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1).
Application:WB IHC
Recommended Dilution:WB 1:1000 - 1:4000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:SH-SY5Y, A375, MCF7, Mouse liver, Mouse skeletal muscle
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGSG EPNP AGKK KKYL KAAL YVGD LDPD VTED MLYK KFRP AGPL RFTR ICRD PVTR SPLG YGYV NFRF PADA EWAL NTMN FDLI NGKP FRLM WSQP DDRL RKSG VGNI FIKN LDKS IDNR ALFY LFSA FGNI LSCK VVCD DNGS KGYA YVHF DSLA AANR AIWH MNGV RLNN RQVY VGRF KFPE ERAA EVRT RDRA TFTN VFVK NIGD DIDD EKLK ELFC EYGP TESV KVIR DASG KSKG FGFV RYET HEAA QKAV LDLH GKSI DGKV LYVG RAQK KIER LAEL RRRF ERLR LKEK SRPP GVPI YIKN LDET INDE KLKE EFSS FGSI SRAK VMME VGQG KGFG VVCF SSFE EATK AVDE MNGR IVGS KPLH VTLG QARR RC
Gene ID:140886
Uniprot:Q96DU9
Cellular Location:Cytoplasm, Mitochondrion matrix
Calculated MW:39kDa/43kDa
Observed MW:43kDa
Synonyms:PABPC5, PABP5
Background:This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
UniProt Protein Function:PABPC5: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: Xq21.3

Cellular Component: mitochondrial matrix

Molecular Function:nucleotide binding; RNA binding

NCBI Summary:This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]
UniProt Code:Q96DU9
NCBI GenInfo Identifier:28201851
NCBI Gene ID:140886
NCBI Accession:Q96DU9.1
UniProt Secondary Accession:Q96DU9,Q5JQF4, Q6P529, Q9UFE5, A8K240,
UniProt Related Accession:Q96DU9
Molecular Weight:39,941 Da
NCBI Full Name:Polyadenylate-binding protein 5
NCBI Synonym Full Names:poly(A) binding protein cytoplasmic 5
NCBI Official Symbol:PABPC5  
NCBI Official Synonym Symbols:PABP5  
NCBI Protein Information:polyadenylate-binding protein 5
UniProt Protein Name:Polyadenylate-binding protein 5
Protein Family:Polyadenylate-binding protein
UniProt Gene Name:PABPC5  
UniProt Entry Name:PABP5_HUMAN
Anti-PABPC5 Polyclonal Antibody (CAB9997)Western blot analysis of extracts of various cell lines, using PABPC5 antibody (CAB9997) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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