Cell Biology Antibodies 6
Anti-OPN3 Antibody (CAB15803)
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- SKU:
- CAB15803
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-OPN3 Antibody |
| Antibody SKU: | CAB15803 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human OPN3 (NP_055137.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | OVCAR3, Mouse brain, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human OPN3 (NP_055137.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SNTV YNPV IYVF MIRK FRRS LLQL LCLR LLRC QRPA KDLP AAGS EMQI RPIV MSQK DGDR PKKK VTFN SSSI IFII TSDE SLSV DDSD KTNG SKVD VIQV R |
| Gene ID: | 23596 |
| Uniprot: | Q9H1Y3 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 35kDa/44kDa |
| Observed MW: | 42kDa |
| Synonyms: | OPN3, ECPN, PPP1R116, opsin-3 |
| Background: | Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. |
| UniProt Protein Function: | encephalopsin: May play a role in encephalic photoreception. Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1q43 Cellular Component: integral to membrane; integral to plasma membrane Molecular Function:G-protein coupled photoreceptor activity; G-protein coupled receptor activity; photoreceptor activity Biological Process: detection of light stimulus; detection of visible light; G-protein coupled receptor protein signaling pathway; phototransduction; protein-chromophore linkage; regulation of circadian rhythm |
| NCBI Summary: | Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H1Y3 |
| NCBI GenInfo Identifier: | 17380172 |
| NCBI Gene ID: | 23596 |
| NCBI Accession: | Q9H1Y3.1 |
| UniProt Secondary Accession: | Q9H1Y3,Q8IX08, Q9Y344, |
| UniProt Related Accession: | Q9H1Y3 |
| Molecular Weight: | 35,730 Da |
| NCBI Full Name: | Opsin-3 |
| NCBI Synonym Full Names: | opsin 3 |
| NCBI Official Symbol: | OPN3 |
| NCBI Official Synonym Symbols: | ECPN; PPP1R116 |
| NCBI Protein Information: | opsin-3 |
| UniProt Protein Name: | Opsin-3 |
| UniProt Synonym Protein Names: | Encephalopsin; Panopsin |
| Protein Family: | Opsin |
| UniProt Gene Name: | OPN3 |
| UniProt Entry Name: | OPN3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OPN3 antibody (CAB15803) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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