Anti-NUP88 Antibody (CAB20729)

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SKU:
CAB20729
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Goat
Isotype:
Fluorescein conjugated IgG

Description

Antibody Name:Anti-NUP88 Antibody (CAB20729)
Antibody SKU:CAB20729
Antibody Size:50µL, 100µL
Application:Western blotting
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2).
Application:Western blotting
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:NCI-H460, Jurkat, U-251MG, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 502-741 of human NUP88 (NP_002523.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SPPL LCTR EDVE VAES PLRV LAET PDSF EKHI RSIL QRSV ANPA FLKA SEKD IAPP PEEC LQLL SRAT QVFR EQYI LKQD LAKE EIQR RVKL LCDQ KKKQ LEDL SYCR EERK SLRE MAER LADK YEEA KEKQ EDIM NRMK KLLH SFHS ELPV LSDS ERDM KKEL QLIP DQLR HLGN AIKQ VTMK KDYQ QQKM EKVL SLPK PTII LSAY QRKC IQSI LKEE GEHI REMV KQIN DIRN HVNF
Cellular Location:
Calculated MW:83kDa
Observed MW:88KDa
Synonyms:FADS4
Background:The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.
Western blot analysis of extracts of various cell lines, using NUP88 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.Western blot analysis of extracts of various cell lines, using NUP88 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
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