Epigenetics & Nuclear Signaling Antibodies 1
Anti-NUP107 Antibody (CAB13110)
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- SKU:
- CAB13110
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-NUP107 Antibody |
| Antibody SKU: | CAB13110 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 766-925 of human NUP107 (NP_065134.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, HeLa, 293T, Jurkat, HepG2, Mouse brain, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 766-925 of human NUP107 (NP_065134.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HMNS VPQK PALI PQPT FTEK VAHE HKEK KYEM DFGI WKGH LDAL TADV KEKM YNVL LFVD GGWM VDVR EDAK EDHE RTHQ MVLL RKLC LPML CFLL HTIL HSTG QYQE CLQL ADMV SSER HKLY LVFS KEEL RKLL QKLR ESSL MLLD QGLD PLGY EIQL |
| Gene ID: | 57122 |
| Uniprot: | P57740 |
| Cellular Location: | Chromosome, Nucleus, Nucleus membrane, centromere, kinetochore, nuclear pore complex |
| Calculated MW: | 79kDa/103kDa/106kDa |
| Observed MW: | 107kDa |
| Synonyms: | NUP107, NPHS11, NUP84 |
| Background: | This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| UniProt Protein Function: | NUP107: Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex. Belongs to the nucleoporin Nup84/Nup107 family. |
| UniProt Protein Details: | Protein type:Nucleoporin Chromosomal Location of Human Ortholog: 12q15 Cellular Component: nucleoplasm; kinetochore; centrosome; nuclear membrane; membrane; nuclear envelope; nuclear pore; cytosol Molecular Function:protein binding; structural constituent of nuclear pore; nucleocytoplasmic transporter activity Biological Process: nuclear pore complex assembly; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; mRNA export from nucleus; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport |
| NCBI Summary: | This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P57740 |
| NCBI GenInfo Identifier: | 12230339 |
| NCBI Gene ID: | 57122 |
| NCBI Accession: | P57740.1 |
| UniProt Secondary Accession: | P57740,Q6PJE1, B4DZ67, |
| UniProt Related Accession: | P57740 |
| Molecular Weight: | 79,971 Da |
| NCBI Full Name: | Nuclear pore complex protein Nup107 |
| NCBI Synonym Full Names: | nucleoporin 107kDa |
| NCBI Official Symbol: | NUP107 |
| NCBI Official Synonym Symbols: | NUP84 |
| NCBI Protein Information: | nuclear pore complex protein Nup107; nucleoporin Nup107; 107 kDa nucleoporin |
| UniProt Protein Name: | Nuclear pore complex protein Nup107 |
| UniProt Synonym Protein Names: | 107 kDa nucleoporin; Nucleoporin Nup107 |
| Protein Family: | Nucleoporin |
| UniProt Gene Name: | NUP107 |
| UniProt Entry Name: | NU107_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NUP107 antibody (CAB13110) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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