Anti-NUDT5 Antibody (CAB0609)
- SKU:
- CAB0609
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NUDT5
- Synonyms:
- YSA1
- Synonyms:
- YSA1H
- Synonyms:
- YSAH1
- Synonyms:
- hNUDT5
- Synonyms:
- nudix hydrolase 5
- Research Area:
- Cell Biology
Description
| Product Name: | NUDT5 Rabbit mAb |
| Product Code: | CAB0609 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NUDT5, YSA1, YSA1H, YSAH1, hNUDT5, nudix hydrolase 5 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human NUDT5. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, A-431, Mouse thymus, Mouse liver, Rat kidney |
| Immunogen: | A synthesized peptide derived from human NUDT5. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 11164 |
| Uniprot: | Q9UKK9 |
| Calculated MW: | 30kDa |
| Observed MW: | 34KDa |
| UniProt Protein Function: | NUDT5: Hydrolyzes with similar activities ADP-ribose ADP- mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. Belongs to the Nudix hydrolase family. |
| UniProt Protein Details: | Protein type:EC 3.6.1.13; EC 3.6.1.58; Nucleotide Metabolism - purine; Phosphatase Chromosomal Location of Human Ortholog: 10p14 Cellular Component: cytosol; nucleus Molecular Function:ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; m7G(5')pppN diphosphatase activity; magnesium ion binding; nucleotidyltransferase activity; protein binding; protein homodimerization activity; snoRNA binding Biological Process: chromatin remodeling; D-ribose catabolic process; ribonucleoside diphosphate catabolic process |
| NCBI Summary: | This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q9UKK9 |
| NCBI GenInfo Identifier: | 20455192 |
| NCBI Gene ID: | 11164 |
| NCBI Accession: | Q9UKK9.1 |
| UniProt Secondary Accession: | Q9UKK9,Q6IAG0, Q9UH49, A8K516, |
| UniProt Related Accession: | Q9UKK9 |
| Molecular Weight: | 24kDa |
| NCBI Full Name: | ADP-sugar pyrophosphatase |
| NCBI Synonym Full Names: | nudix hydrolase 5 |
| NCBI Official Symbol: | NUDT5 |
| NCBI Official Synonym Symbols: | YSA1; YSA1H; YSAH1; hNUDT5 |
| NCBI Protein Information: | ADP-sugar pyrophosphatase |
| UniProt Protein Name: | ADP-sugar pyrophosphatase |
| UniProt Synonym Protein Names: | 8-oxo-dGDP phosphatase (EC:3.6.1.58 |
| Protein Family: | Nudix hydrolase |
| UniProt Gene Name: | NUDT5 |
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