Description
Antibody Name: | Anti-NPY5R Antibody (CAB9359) |
Antibody SKU: | CAB9359 |
Antibody Size: | 50µL, 100µL |
Application: | Western blotting, Immunofluorescence |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human NPY5R. |
Application: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | DU145, K-562, SH-SY5Y, Mouse brain, Mouse eye, Rat spinal cord, Rat brain |
Immunogen: | A synthesized peptide derived from human NPY5R. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Cellular Location: | |
Calculated MW: | 51kDa |
Observed MW: | 50KDa |
Synonyms: | |
Background: | The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. |
Immunofluorescence analysis of Neuro-2a cells using NPY5R Rabbit mAb at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. | |
Immunofluorescence analysis of SH-SY5Y cells using NPY5R Rabbit mAb at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. | |
Western blot analysis of extracts of various cell lines, using at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 0. 5s. |