Cell Biology Antibodies 5

NOS1 Rabbit Polyclonal Antibody (CAB1485)

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SKU:
CAB1485
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Synonyms:
NOS, bNOS, nNOS, IHPS1, N-NOS, NC-NOS, NOS1
Research Use:
Cell Biology
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Description

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NOS1 Antibody (CAB1485)

The NOS1 Antibody (CAB1485) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically designed for use in studies involving NOS1 in human samples and has been validated for Western blot applications.NOS1, also known as neuronal nitric oxide synthase, plays a key role in neurotransmission, vasodilation, and immune response modulation. Dysregulation of NOS1 activity has been implicated in various diseases such as neurodegenerative disorders, cardiovascular diseases, and inflammatory conditions.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.

Product Name:NOS1 Antibody
SKU:CAB1485
Size:20μL, 100μL
Reactivity:Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MEDH MFGV QQIQ PNVI SVRL FKRK VGGL GFLV KERV SKPP VIIS DLIR GGAA EQSG LIQA GDII LAVN GRPL VDLS YDSA LEVL RGIA SETH VVLI LRGP EGFT THLE TTFT GDGT PKTI RVTQ PLGP PTKA VDLS HQPP AGKE QPLA VDGA SGPG NGPQ HAYD DGQE AGSL PHAN GLAP
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:NOS, bNOS, nNOS, IHPS1, N-NOS, NC-NOS, NOS1
Positive Sample:Rat liver
Cellular Localization:Cell Membrane, Cell Projection, Peripheral Membrane Protein, Dendritic Spine, Sarcolemma.
Calculated MW:161kDa
Observed MW:160kDa

The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.

Purification MethodAffinity purification
Gene ID4842
RRIDAB_2761730
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from rat liver, using NOS1 Rabbit pAb (CAB1485) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
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