Cell Death Antibodies 1
Anti-NME3 Antibody (CAB2774)
- SKU:
- CAB2774
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Description
Antibody Name: | Anti-NME3 Antibody |
Antibody SKU: | CAB2774 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-169 of human NME3 (NP_002504.2). |
Application: | WB IHC IF |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | THP-1, Raji, Mouse kidney, Mouse liver |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-169 of human NME3 (NP_002504.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | AHER TFLA VKPD GVQR RLVG EIVR RFER KGFK LVAL KLVQ ASEE LLRE HYAE LRER PFYG RLVK YMAS GPVV AMVW QGLD VVRT SRAL IGAT NPAD APPG TIRG DFCI EVGK NLIH GSDS VESA RREI ALWF RADE LLCW EDSA GHWL YE |
Gene ID: | 4832 |
Uniprot: | Q13232 |
Cellular Location: | |
Calculated MW: | 19kDa |
Observed MW: | 19kDa |
Synonyms: | NME3, DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2 |
Background: |
UniProt Protein Function: | NME3: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. Belongs to the NDK family. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Apoptosis; Nucleotide Metabolism - purine; Kinase, nucleoside diphosphate; Motility/polarity/chemotaxis; Kinase, other; Other group; NDK family Chromosomal Location of Human Ortholog: 16q13.3 Cellular Component: mitochondrion; cytosol Molecular Function:metal ion binding; nucleoside diphosphate kinase activity; ATP binding Biological Process: GTP biosynthetic process; regulation of apoptosis; CTP biosynthetic process; pyrimidine nucleotide metabolic process; apoptosis; UTP biosynthetic process; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; purine nucleotide metabolic process |
UniProt Code: | Q13232 |
NCBI GenInfo Identifier: | 21264477 |
NCBI Gene ID: | 4832 |
NCBI Accession: | Q13232.2 |
UniProt Secondary Accession: | Q13232,Q9BWH4, |
UniProt Related Accession: | Q13232 |
Molecular Weight: | 19,015 Da |
NCBI Full Name: | Nucleoside diphosphate kinase 3 |
NCBI Synonym Full Names: | NME/NM23 nucleoside diphosphate kinase 3 |
NCBI Official Symbol: | NME3 |
NCBI Official Synonym Symbols: | NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2 |
NCBI Protein Information: | nucleoside diphosphate kinase 3; NDK 3; NDP kinase 3; NDP kinase C; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase C |
UniProt Protein Name: | Nucleoside diphosphate kinase 3 |
UniProt Synonym Protein Names: | DR-nm23; Nucleoside diphosphate kinase C; NDPKC; nm23-H3 |
Protein Family: | Nucleoside diphosphate kinase |
UniProt Gene Name: | NME3 |
UniProt Entry Name: | NDK3_HUMAN |
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