Cell Biology Antibodies 12

Anti-NLRP5 Antibody (CAB9886)

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SKU:
CAB9886
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-NLRP5 Antibody
Antibody SKU:CAB9886
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 157-256 of human NLRP5 (NP_703148.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 157-256 of human NLRP5 (NP_703148.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:TMTD QGPS KEKV PGIS QAVQ QDSA TAAE TKEQ EISQ AMEQ EGAT AAET EEQE ISQA MEQE GATA AETE EQGH GGDT WDYK SHVM TKFA EEED VRRS FENT
Gene ID:126206
Uniprot:P59047
Cellular Location:Cytoplasm, Mitochondrion, Nucleus, nucleolus
Calculated MW:134kDa
Observed MW:134kDa
Synonyms:NLRP5, CLR19.8, MATER, NALP5, PAN11, PYPAF8
Background:The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis.
UniProt Protein Function:NLRP5: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. Belongs to the NLRP family.
UniProt Protein Details:

Protein type:Nucleolus

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: mitochondrion; nucleolus

NCBI Summary:The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]
UniProt Code:P59047
NCBI GenInfo Identifier:215274029
NCBI Gene ID:126206
NCBI Accession:P59047.2
UniProt Secondary Accession:P59047,Q86W29, A8MTY4,
UniProt Related Accession:P59047
Molecular Weight:134kDa
NCBI Full Name:NACHT, LRR and PYD domains-containing protein 5
NCBI Synonym Full Names:NLR family pyrin domain containing 5
NCBI Official Symbol:NLRP5  
NCBI Official Synonym Symbols:MATER; NALP5; PAN11; PYPAF8; CLR19.8  
NCBI Protein Information:NACHT, LRR and PYD domains-containing protein 5
UniProt Protein Name:NACHT, LRR and PYD domains-containing protein 5
UniProt Synonym Protein Names:Mater protein homolog
Protein Family:NACHT, LRR and PYD domains-containing protein
UniProt Gene Name:NLRP5  
Anti-NLRP5 Polyclonal Antibody (CAB9886)Western blot analysis of extracts of SKOV3 cells, using NLRP5 Antibody (CAB9886) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20S.
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