Signal Transduction Antibodies 1
Anti-NGDN Antibody (CAB14509)
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- SKU:
- CAB14509
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-NGDN Antibody |
| Antibody SKU: | CAB14509 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-209 of human NGDN (NP_001036100.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-209 of human NGDN (NP_001036100.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LMYL MDLT HLIL DKAS GGSL QGHD AVLR LVEI RTVL EKLR PLDQ KLKY QIDK LIKT AVTG SLSE NDPL RFKP HPSN MMSK LSSE DEEE DEAE DDQS EASG KKSV KGVS KKYV PPRL VPVH YDET EAER EKKR LERA KRRA LSSS VIRE L |
| Gene ID: | 25983 |
| Uniprot: | Q8NEJ9 |
| Cellular Location: | Cell projection, Chromosome, Cytoplasm, Nucleus, axon, centromere, dendrite, filopodium, nucleolus |
| Calculated MW: | 35kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | NGDN, C14orf120, CANu1, LCP5, NGD, lpd-2 |
| Background: |
| UniProt Protein Function: | NGDN: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. Belongs to the SAS10 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; Translation; Nucleolus Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: nucleolus; small subunit processome Molecular Function:protein binding Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| NCBI Summary: | Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NEJ9 |
| NCBI GenInfo Identifier: | 46395905 |
| NCBI Gene ID: | 25983 |
| NCBI Accession: | Q8NEJ9.1 |
| UniProt Secondary Accession: | Q8NEJ9,Q9Y400, A8K760, |
| UniProt Related Accession: | Q8NEJ9 |
| Molecular Weight: | 35,250 Da |
| NCBI Full Name: | Neuroguidin |
| NCBI Synonym Full Names: | neuroguidin |
| NCBI Official Symbol: | NGDN |
| NCBI Official Synonym Symbols: | NGD; LCP5; CANu1; lpd-2; C14orf120 |
| NCBI Protein Information: | neuroguidin |
| UniProt Protein Name: | Neuroguidin |
| UniProt Synonym Protein Names: | Centromere accumulated nuclear protein 1; CANu1; EIF4E-binding protein |
| Protein Family: | Neuroguidin |
| UniProt Gene Name: | NGDN |
| UniProt Entry Name: | NGDN_HUMAN |
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