Cell Biology Antibodies 17
Neurokinin 1 Receptor (NK1R) Rabbit Monoclonal Antibody (CAB4676)
- SKU:
- CAB4676
- Product Type:
- Antibody
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human, Mouse, Rat
- Synonyms:
- SPR, NK1R, NKIR, TAC1R, Neurokinin 1 Receptor (NK1R)
- Research Use:
- Cell Biology
Description
Neurokinin 1 Receptor (NK1R) Monoclonal Antibody (CAB4676)
The Neurokinin 1 Receptor (NK1R) Monoclonal Antibody (CAB4676) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.The NK-1R is a G protein-coupled receptor that binds the neuropeptide substance P, helping to transmit pain signals and modulate inflammatory responses. Its role in pain perception and neuroinflammation makes it a promising target for drug development in pain management and inflammatory disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
| Product Name: | Neurokinin 1 Receptor (NK1R) Monoclonal Antibody |
| SKU: | CAB4676 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Mouse, Rat |
| Clone Number: | ARC1088 |
| Conjugate: | Unconjugated |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. | ||||
| Sequence: | YNPI IYCC LNDR FRLG FKHA FRCC PFIS AGDY EGLE MKST RYLQ TQGS VYKV SRLE TTIS TVVG AHEE EPED GPKA TPSS LDLT SNCS SRSD SKTM TESF SFSS NVLS | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
| ||||
| Synonyms: | SPR, NK1R, NKIR, TAC1R, Neurokinin 1 Receptor (NK1R) |
| Positive Sample: | HeLa, SH-SY5Y, Mouse brain, Rat brain, Rat spleen |
| Cellular Localization: | Cell Membrane, Multi-Pass Membrane Protein. |
| Calculated MW: | 46kDa |
| Observed MW: | 50kDa |
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.
| Purification Method | Affinity purification |
| Gene ID | 6869 |
| RRID | AB_2863320 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using Neurokinin 1 Receptor (NK1R) (NK1R) Rabbit mAb (CAB4676) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s. |
 | Western blot analysis of various lysates using Neurokinin 1 Receptor (NK1R) (NK1R) Rabbit mAb (CAB4676) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s. |
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