Developmental Biology

Anti-NEUROG1 Antibody (CAB3110)

(No reviews yet) Write a Review
SKU:
CAB3110
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-NEUROG1 Antibody
Antibody SKU:CAB3110
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide of human NEUROG1
Application:WB
Recommended Dilution:WB 1:500 - 1:1000
Reactivity:Human, Mouse
Positive Samples:SH-SY5Y, THP-1, U-87MG, HepG2, Mouse testis
Immunogen:A synthetic peptide of human NEUROG1
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4762
Uniprot:Q92886
Cellular Location:Nucleus
Calculated MW:25kDa
Observed MW:25kDa
Synonyms:NEUROG1, AKA, Math4C, NEUROD3, bHLHa6, ngn1
Background:
UniProt Protein Function:neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.
UniProt Protein Details:

Protein type:Transcription factor; Cell development/differentiation; DNA-binding

Chromosomal Location of Human Ortholog: 5q23-q31

Cellular Component: perikaryon; nucleus

Molecular Function:protein dimerization activity; DNA binding; chromatin binding; transcription factor activity

Biological Process: neuron differentiation; regulation of transcription from RNA polymerase II promoter; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; positive regulation of exit from mitosis

UniProt Code:Q92886
NCBI GenInfo Identifier:37538313
NCBI Gene ID:4762
NCBI Accession:Q92886.2
UniProt Related Accession:Q92886
Molecular Weight:
NCBI Full Name:Neurogenin-1
NCBI Synonym Full Names:neurogenin 1
NCBI Official Symbol:NEUROG1  
NCBI Official Synonym Symbols:AKA; ngn1; Math4C; bHLHa6; NEUROD3  
NCBI Protein Information:neurogenin-1
UniProt Protein Name:Neurogenin-1
UniProt Synonym Protein Names:Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3
UniProt Gene Name:NEUROG1  
UniProt Entry Name:NGN1_HUMAN
Anti-NEUROG1 Antibody (CAB3110)Western blot analysis of extracts of various cell lines, using NEUROG1 antibody (CAB3110) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
View AllClose

0 Reviews

View AllClose

Related Products